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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/17717
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dc.contributor.authorAldape, Kenneth-
dc.contributor.authorAmin, Samirkumar B-
dc.contributor.authorAshley, David M-
dc.contributor.authorBarnholtz-Sloan, Jill S-
dc.contributor.authorBates, Amanda J-
dc.contributor.authorBeroukhim, Rameen-
dc.contributor.authorBock, Christoph-
dc.contributor.authorBrat, Daniel J-
dc.contributor.authorClaus, Elizabeth B-
dc.contributor.authorCostello, Joseph F-
dc.contributor.authorde Groot, John F-
dc.contributor.authorFinocchiaro, Gaetano-
dc.contributor.authorFrench, Pim J-
dc.contributor.authorGan, Hui K-
dc.contributor.authorGriffith, Brent-
dc.contributor.authorHerold-Mende, Christel C-
dc.contributor.authorHorbinski, Craig-
dc.contributor.authorIavarone, Antonio-
dc.contributor.authorKalkanis, Steven N-
dc.contributor.authorKarabatsou, Konstantina-
dc.contributor.authorKim, Hoon-
dc.contributor.authorKouwenhoven, Mathilde C M-
dc.contributor.authorMcDonald, Kerrie L-
dc.contributor.authorMiletic, Hrvoje-
dc.contributor.authorNam, Do-Hyun-
dc.contributor.authorNg, Ho Keung-
dc.contributor.authorNiclou, Simone P-
dc.contributor.authorNoushmehr, Houtan-
dc.contributor.authorOrmond, Ryan-
dc.contributor.authorPoisson, Laila M-
dc.contributor.authorReifenberger, Guido-
dc.contributor.authorRoncaroli, Federico-
dc.contributor.authorSa, Jason K-
dc.contributor.authorSillevis Smitt, Peter A E-
dc.contributor.authorSmits, Marion-
dc.contributor.authorSouza, Camila F-
dc.contributor.authorTabatabai, Ghazaleh-
dc.contributor.authorVan Meir, Erwin G-
dc.contributor.authorVerhaak, Roel G W-
dc.contributor.authorWatts, Colin-
dc.contributor.authorWesseling, Pieter-
dc.contributor.authorWoehrer, Adelheid-
dc.contributor.authorYung, W K Alfred-
dc.contributor.authorJungk, Christine-
dc.contributor.authorHau, Ann-Christin-
dc.contributor.authorvan Dyck, Eric-
dc.contributor.authorWesterman, Bart A-
dc.contributor.authorYin, Julia-
dc.contributor.authorAbiola, Olajide-
dc.contributor.authorZeps, Nikolaj-
dc.contributor.authorGrimmond, Sean-
dc.contributor.authorBuckland, Michael-
dc.contributor.authorKhasraw, Mustafa-
dc.contributor.authorSulman, Erik P-
dc.contributor.authorMuscat, Andrea M-
dc.contributor.authorStead, Lucy-
dc.date2018-02-08-
dc.date.accessioned2018-05-15T06:33:55Z-
dc.date.available2018-05-15T06:33:55Z-
dc.date.issued2018-02-08-
dc.identifier.citationNeuro-oncology 2018; online first: 8 February-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/17717-
dc.description.abstractAdult diffuse gliomas are a diverse group of brain neoplasms that inflict a high emotional toll on patients and their families. The Cancer Genome Atlas (TCGA) and similar projects have provided a comprehensive understanding of the somatic alterations and molecular subtypes of glioma at diagnosis. However, gliomas undergo significant cellular and molecular evolution during disease progression. We review the current knowledge on the genomic and epigenetic abnormalities in primary tumors and after disease recurrence, highlight the gaps in the literature, and elaborate on the need for a new multi-institutional effort to bridge these knowledge gaps and how the Glioma Longitudinal AnalySiS Consortium (GLASS) aims to systemically catalog the longitudinal changes in gliomas. The GLASS initiative will provide essential insights into the evolution of glioma toward a lethal phenotype, with the potential to reveal targetable vulnerabilities, and ultimately, improved outcomes for a patient population in need.-
dc.language.isoeng-
dc.subjectcharacterization-
dc.subjectevolution-
dc.subjectglioma-
dc.subjectsequencing-
dc.subjectsubtypes-
dc.titleGlioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium.-
dc.typeJournal Article-
dc.identifier.journaltitleNeuro-oncology-
dc.identifier.affiliationDepartment of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canadaen
dc.identifier.affiliationJackson Laboratory for Genomic Medicine, Ten Discovery Drive, Farmington, CT, USAen
dc.identifier.affiliationPreston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, NC, USA-
dc.identifier.affiliationCase Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA-
dc.identifier.affiliationNational Brain Tumor Society, Newton, MA, USA-
dc.identifier.affiliationDepartments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA-
dc.identifier.affiliationCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria-
dc.identifier.affiliationDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA-
dc.identifier.affiliationYale School of Public Health, New Haven, CT, and Department of Neurosurgery, Brigham and Women's Hospital, Boston, MA, USA-
dc.identifier.affiliationUniversity of California San Francisco, San Francisco, CA, USA-
dc.identifier.affiliationUniversity of Texas, MD, and Anderson Cancer Center, Houston, TX, USA-
dc.identifier.affiliationFondazione IRCCS Istituto Neurologico Besta, Milano, Italy-
dc.identifier.affiliationDepartment of Neurology, Erasmus MC, Rotterdam, The Netherlands-
dc.identifier.affiliationOlivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia-
dc.identifier.affiliationDepartment of Radiology, Henry Ford Health System, Detroit, MI, USA-
dc.identifier.affiliationDivision of Experimental Neurosurgery, Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany-
dc.identifier.affiliationDepartment of Neurology, Department of Pathology, Institute for Cancer Genetics, Columbia University Medical Center, New York, USA-
dc.identifier.affiliationDepartment of Neurosurgery, Henry Ford Health System, Detroit, MI, USA-
dc.identifier.affiliationSalford Royal Hospital, Stott Lane, Greater Manchester, UK-
dc.identifier.affiliationDepartment of Neurology, VU University Medical Center/Brain Tumor Center, Amsterdam, The Netherlands-
dc.identifier.affiliationCure Brain Cancer Biomarkers and Translational Research Group, Prince of Wales Clinical School, University of NSW, Sydney, Australia-
dc.identifier.affiliationDepartment of Pathology, Haukeland University Hospital, Bergen, Norway-
dc.identifier.affiliationDepartment of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea-
dc.identifier.affiliationDepartment of Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong-
dc.identifier.affiliationLuxembourg Institute of Health, NorLux Neuro-Oncology Laboratory, Luxembourg-
dc.identifier.affiliationDepartment of Neurosurgery, University of Colorado School of Medicine, Aurora, CO, USA-
dc.identifier.affiliationDepartment of Neuropathology, Heinrich Heine University Duesseldorf Medical Faculty, Duesseldorf, Germany-
dc.identifier.affiliationDivision of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, UK-
dc.identifier.affiliationResearch Institute for Future Medicine, Samsung Medical Center, Seoul, Korea-
dc.identifier.affiliationDepartment of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands-
dc.identifier.affiliationDepartment of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands-
dc.identifier.affiliationInterdisciplinary Division of Neuro-Oncology, Departments of Neurology and Neurosurgery, University Hospital, Tübingen, Germany-
dc.identifier.affiliationDepartments of Neurosurgery, Hematology, and Medical Oncology, School of Medicine, and Winship Cancer Institute, Emory University, Atlanta, GA, USA-
dc.identifier.affiliationDepartment of Clinical Neurosciences, Division of Neurosurgery, University of Cambridge, UK-
dc.identifier.affiliationDepartment of Pathology, VU University Medical Center/Brain Tumor Center Amsterdam, Amsterdam, The Netherlands-
dc.identifier.affiliationInstitute of Neurology, Medical University of Vienna, Vienna, Austria-
dc.identifier.affiliationAnderson Cancer Center, Houston, TX, USA-
dc.identifier.affiliationDepartment of Neurosurgery, University of Heidelberg, Heidelberg, Germany-
dc.identifier.affiliationBrain Tumor Center Amsterdam, Cancer Center Amsterdam, VU Medical Center, Amsterdam, The Netherlands-
dc.identifier.affiliationCure Brain Cancer Biomarkers and Translational Research Group, Prince of Wales Clinical School, University of NSW, Australia-
dc.identifier.affiliationMonash University and Epworth Health, Melbourne, Victoria, Australia-
dc.identifier.affiliationUniversity of Melbourne and Victorian Comprehensive Cancer Centre, Melbourne, Victoria, Australia-
dc.identifier.affiliationRoyal Prince Alfred Hospital and University of Sydney, NSW, Australia-
dc.identifier.affiliationUniversity of Sydney, NSW, Australia-
dc.identifier.affiliationUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA-
dc.identifier.affiliationDeakin University, Geelong, Victoria, Australia-
dc.identifier.affiliationSt James's University Hospital, Leeds, UK-
dc.identifier.affiliationPrincess Máxima Center for Pediatric Oncology and University Medical Center Utrecht, The Netherlands-
dc.identifier.doi10.1093/neuonc/noy020-
dc.identifier.pubmedid29432615-
dc.type.austinJournal Article-
local.name.researcherGan, Hui K
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.languageiso639-1en-
item.cerifentitytypePublications-
crisitem.author.deptMedical Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
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