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dc.contributor.authorMiller, Dorothea-
dc.contributor.authorCarney, Patrick W-
dc.contributor.authorArcher, John S-
dc.contributor.authorFitt, Gregory J-
dc.contributor.authorJackson, Graeme D-
dc.contributor.authorBulluss, Kristian J-
dc.identifier.citationJournal of Clinical Neuroscience 2017; 48: 191-195en_US
dc.description.abstractBottom of sulcus dysplasias (BOSDs) are localized focal cortical dysplasias (FCDs) centred on the bottom of a sulcus that can be highly epileptogenic, but difficult to delineate intraoperatively. We report on a patient with refractory epilepsy due to a BOSD, successfully resected with the aid of a multimodal surgical approach using neuronavigation based on MRI and PET, intraoperative ultrasound (iUS) and electrocorticography (ECoG) using depth electrodes. The lesion could be visualized on iUS showing an increase in echogenicity at the grey-white matter junction. IUS demonstrated the position of the depth electrode in relation to the lesion. Depth electrode recording showed almost continuous spiking. Thus, intraoperative imaging and electrophysiology helped confirm the exact location of the lesion. Post-resection ultrasound demonstrated the extent of the resection and depth electrode recording did not show any epileptiform activity. Thus, both techniques helped assess completeness of resection. The patient has been seizure free since surgery. Using a multimodal approach including iUS and ECoG is a helpful adjunct in surgery for BOSD and may improve seizure outcome.en_US
dc.subjectBottom-of-sulcus dysplasiaen_US
dc.subjectDepth electrodesen_US
dc.subjectFocal cortical dysplasiaen_US
dc.subjectIntraoperative ultrasounden_US
dc.titleIntraoperative definition of bottom-of-sulcus dysplasia using intraoperative ultrasound and single depth electrode recording - A technical noteen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleJournal of Clinical Neuroscienceen_US
dc.identifier.affiliationDepartment of Neurosurgery, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Neurology, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Radiology, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationEastern Health Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Box Hill, Victoria, Australiaen_US
dc.identifier.affiliationUniversity of Melbourne, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationThe Florey Institute of Neuroscience and Mental Health, Melbourne Brain Centre, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Neurosurgery, Essen University Hospital, Essen, Nordrhein-Westfalen, Germanyen_US
dc.type.austinJournal Articleen_US, John S
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.openairecristype Research Centre- Florey Institute of Neuroscience and Mental Health-
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