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dc.contributor.authorPatwala, Kurvi-
dc.contributor.authorCrump, Nicholas H-
dc.contributor.authorDe Cruz, Peter-
dc.identifier.citationBMJ Case Reports 2017; online first: 5 Julyen
dc.description.abstractGuillain-Barré syndrome (GBS) is an immune-mediated disease characterised by evolving ascending limb weakness, sensory loss and areflexia. Two-thirds of GBS cases are associated with preceding infection. However, GBS has also been described in association with antitumour necrosis factor (TNF) therapies including infliximab and adalimumab for chronic inflammatory disorders such as rheumatoid arthritis, ankylosing spondylitis and inflammatory bowel disease. We present the case of a patient who developed GBS while undergoing treatment with adalimumab in combination with azathioprine for severe fistulising Crohn's disease, and review the literature on neurological adverse events that occur in association with anti-TNF therapy. We also propose an approach to the optimal management of patients who develop debilitating neurological sequelae in the setting of anti-TNF therapy.en
dc.subjectContraindications and precautionsen
dc.subjectGastrointestinal systemen
dc.subjectInflammatory bowel diseaseen
dc.subjectNeurology (drugs and medicines)en
dc.subjectPeripheral nerve diseaseen
dc.titleGuillain-Barré syndrome in association with antitumour necrosis factor therapy: a case of mistaken identityen
dc.typeJournal Articleen
dc.identifier.journaltitleBMJ Case Reportsen
dc.identifier.affiliationDepartment of Gastroenterology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Neurology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Medicine, The University of Melbourne, Melbourne, Australiaen
dc.type.studyortrialCase Series and Case Reportsen
dc.type.austinJournal Articleen_US
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.openairecristype (University of Melbourne)-
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