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https://ahro.austin.org.au/austinjspui/handle/1/16668
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DC Field | Value | Language |
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dc.contributor.author | Traenka, Christopher | - |
dc.contributor.author | Dougoud, Daphne | - |
dc.contributor.author | Simonetti, Barbara Goeggel | - |
dc.contributor.author | Metso, Tiina M | - |
dc.contributor.author | Debette, Stephanie | - |
dc.contributor.author | Pezzini, Alessandro | - |
dc.contributor.author | Kloss, Manja | - |
dc.contributor.author | Grond-Ginsbach, Caspar | - |
dc.contributor.author | Majersik, Jennifer J | - |
dc.contributor.author | Worrall, Bradford B | - |
dc.contributor.author | Leys, Didier | - |
dc.contributor.author | Baumgartner, Ralf | - |
dc.contributor.author | Caso, Valeria | - |
dc.contributor.author | Bejot, Yannick | - |
dc.contributor.author | Compter, Annette | - |
dc.contributor.author | Reiner, Peggy | - |
dc.contributor.author | Thijs, Vincent | - |
dc.contributor.author | Southerland, Andrew M | - |
dc.contributor.author | Bersano, Anna | - |
dc.contributor.author | Brandt, Tobias | - |
dc.contributor.author | Gensicke, Henrik | - |
dc.contributor.author | Touze, Emmanuel | - |
dc.contributor.author | Martin, Juan J | - |
dc.contributor.author | Chabriat, Hugues | - |
dc.contributor.author | Tatlisumak, Turgut | - |
dc.contributor.author | Lyrer, Philippe | - |
dc.contributor.author | Arnold, Marcel | - |
dc.contributor.author | Engelter, Stefan T | - |
dc.contributor.author | CADISP-Plus Study Group | - |
dc.date | 2017-04-04 | - |
dc.date.accessioned | 2017-06-01T05:58:12Z | - |
dc.date.available | 2017-06-01T05:58:12Z | - |
dc.date.issued | 2017-04-04 | - |
dc.identifier.citation | Neurology 2017; 88(14): 1313-1320 | en_US |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/16668 | - |
dc.description.abstract | OBJECTIVE: In a cohort of patients diagnosed with cervical artery dissection (CeAD), to determine the proportion of patients aged ≥60 years and compare the frequency of characteristics (presenting symptoms, risk factors, and outcome) in patients aged <60 vs ≥60 years. METHODS: We combined data from 3 large cohorts of consecutive patients diagnosed with CeAD (i.e., Cervical Artery Dissection and Ischemic Stroke Patients-Plus consortium). We dichotomized cases into 2 groups, age ≥60 and <60 years, and compared clinical characteristics, risk factors, vascular features, and 3-month outcome between the groups. First, we performed a combined analysis of pooled individual patient data. Secondary analyses were done within each cohort and across cohorts. Crude and adjusted odds ratios (OR [95% confidence interval]) were calculated. RESULTS: Among 2,391 patients diagnosed with CeAD, we identified 177 patients (7.4%) aged ≥60 years. In this age group, cervical pain (ORadjusted 0.47 [0.33-0.66]), headache (ORadjusted 0.58 [0.42-0.79]), mechanical trigger events (ORadjusted 0.53 [0.36-0.77]), and migraine (ORadjusted 0.58 [0.39-0.85]) were less frequent than in younger patients. In turn, hypercholesterolemia (ORadjusted 1.52 [1.1-2.10]) and hypertension (ORadjusted 3.08 [2.25-4.22]) were more frequent in older patients. Key differences between age groups were confirmed in secondary analyses. In multivariable, adjusted analyses, favorable outcome (i.e., modified Rankin Scale score 0-2) was less frequent in the older age group (ORadjusted 0.45 [0.25, 0.83]). CONCLUSION: In our study population of patients diagnosed with CeAD, 1 in 14 was aged ≥60 years. In these patients, pain and mechanical triggers might be missing, rendering the diagnosis more challenging and increasing the risk of missed CeAD diagnosis in older patients. | en_US |
dc.subject | Neck Pain | en_US |
dc.subject | Vertebral Artery Dissection | en_US |
dc.title | Cervical artery dissection in patients ≥60 years: often painless, few mechanical triggers | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | Neurology | en_US |
dc.identifier.affiliation | Department of Neurology and Stroke Center, University Hospital Basel and University of Basel, Switzerland | en_US |
dc.identifier.affiliation | Department of Neurology, University Hospital Berne, Berne, Switzerland | en_US |
dc.identifier.affiliation | Ospedale San Giovanni, Bellinzona, Switzerland | en_US |
dc.identifier.affiliation | Department of Neurology, Helsinki University Central Hospital, Finland | en_US |
dc.identifier.affiliation | Department of Neurology, Bordeaux University Hospital, Bordeaux, France | en_US |
dc.identifier.affiliation | Inserm U1219, Bordeaux | en_US |
dc.identifier.affiliation | Bordeaux University, Bordeaux, France | en_US |
dc.identifier.affiliation | Department of Neurology, Boston University School of Medicine, Boston, MA, USA | en_US |
dc.identifier.affiliation | Department of Clinical and Experimental Sciences, Neurology Clinic, University of Brescia, Brescia, Italy | en_US |
dc.identifier.affiliation | Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany | en_US |
dc.identifier.affiliation | Department of Neurology, University of Utah, Salt Lake City, UT, USA | en_US |
dc.identifier.affiliation | Departments of Neurology and Public Health Sciences, University of Virginia Health System, Charlottesville, VA, USA | en_US |
dc.identifier.affiliation | Univ Lille 2, INSERM U 1171, CHU Lille, France | en_US |
dc.identifier.affiliation | Neuro Center, Clinic Hirslanden, Zurich, Switzerland | en_US |
dc.identifier.affiliation | Stroke Unit and Division of Internal and Cardiovascular Medicine, University of Perugia, Italy | en_US |
dc.identifier.affiliation | Centre Hospitalier Universitaire Le Bocage, Dijon, France | en_US |
dc.identifier.affiliation | Department of Neurology and Neurosurgery, Brain Centre Rudolf Magnus, University Medical Centre Utrecht, the Netherlands | en_US |
dc.identifier.affiliation | Department of Neurology, Lariboisière Hospital, Paris 7 University, DHU Neurovasc Sorbonne Paris Cité, France | en_US |
dc.identifier.affiliation | Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia | en_US |
dc.identifier.affiliation | Department of Neurology, Austin Health, Heidelberg, Victoria, Australia | en_US |
dc.identifier.affiliation | Cerebrovascular Unit, IRCCS Foundation C. Besta Neurological Institute, Milan, Italy | en_US |
dc.identifier.affiliation | Clinics for Neurologic Rehabilitation, Kliniken Schmieder, Heidelberg, Germany | en_US |
dc.identifier.affiliation | Normandie Univ, UNICAEN, Inserm U919, Department of Neurology, CHU Caen, France | en_US |
dc.identifier.affiliation | Department of Neurology, CH Sainte-Anne, University Paris Descartes, France | en_US |
dc.identifier.affiliation | Department of Neurology, Sanatorio Allende, Cordoba, Argentina | en_US |
dc.identifier.affiliation | Department of Neurology, Sahlgrenska University Hospital and Institute for Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Sweden | en_US |
dc.identifier.affiliation | Neurorehabilitation Unit, University of Basel and University Center for Medicine of Aging and Rehabilitation, Felix Platter Hospital, Basel, Switzerland | en_US |
dc.identifier.pubmeduri | https://pubmed.ncbi.nlm.nih.gov/28258079 | en_US |
dc.identifier.doi | 10.1212/WNL.0000000000003788 | en_US |
dc.type.content | Text | en_US |
dc.type.austin | Journal Article | en_US |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.openairetype | Journal Article | - |
item.grantfulltext | none | - |
Appears in Collections: | Journal articles |
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