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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16564
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dc.contributor.authorSabbagh, Marwan N-
dc.contributor.authorSchäuble, Barbara-
dc.contributor.authorAnand, Keshav-
dc.contributor.authorRichards, Danielle-
dc.contributor.authorMurayama, Shigeo-
dc.contributor.authorAkatsu, Hiroyasu-
dc.contributor.authorTakao, Masaki-
dc.contributor.authorRowe, Christopher C-
dc.contributor.authorMasters, Colin L-
dc.contributor.authorBarthel, Henryk-
dc.contributor.authorGertz, Hermann-Josef-
dc.contributor.authorPeters, Oliver-
dc.contributor.authorRasgon, Natalie-
dc.contributor.authorJovalekic, Aleksandar-
dc.contributor.authorSabri, Osama-
dc.contributor.authorSchulz-Schaeffer, Walter-
dc.contributor.authorSeibyl, John-
dc.date.accessioned2017-02-02T05:45:24Z-
dc.date.available2017-02-02T05:45:24Z-
dc.date.issued2017-01-24-
dc.identifier.citationJournal of Alzheimer's Disease 2017; 56(2): 441-446en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/16564-
dc.description.abstractOf 57 individuals diagnosed with Alzheimer’s disease (AD) in a phase III study, 13 (23%) had amyloid-β (Aβ) levels on postmortem histopathology that did not explain the dementia. Based on postmortem histopathology, a wide range of different non-AD conditions was identified, including frontotemporal dementia, hippocampal sclerosis, and dementia with Lewy bodies. Of the histopathologically Aβ negative scored cases ante-mortem Florbetaben PET scans were classified as negative for Aβ in 11 patients based on visual analysis and in all 12 quantifiable cases based on composite standardized uptake value ratios. Thus, florbetaben PET can assist physicians in the differential diagnosis of neurodegenerative disorders by reliably excluding Aβ pathology.en_US
dc.subjectAlzheimer’s diseaseen_US
dc.subjectFlorbetaben PETen_US
dc.subjectHistopathologyen_US
dc.titleHistopathology and florbetaben PET in patients incorrectly diagnosed with Alzheimer's diseaseen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleJournal of Alzheimer's Diseaseen_US
dc.identifier.affiliationAlzheimer’s and Memory Disorders Division, Barrow Neurological Institute, Phoenix, AZ, USAen_US
dc.identifier.affiliationFormerly Piramal Imaging GmbH, Berlin, Germanyen_US
dc.identifier.affiliationBanner Sun Health Research Institute, Sun City, AZ, USAen_US
dc.identifier.affiliationTokyo Metropolitan Geriatric Hospital, Tokyo, Japanen_US
dc.identifier.affiliationTokyo Metropolitan Institute of Gerontology, Tokyo, Japanen_US
dc.identifier.affiliationFukushimura Hospital, Toyohashi, Japanen_US
dc.identifier.affiliationDepartments of Community-based Medicine and Neurology, Nagoya City University Graduate School of Medical Sciences, Nagoya City, Aichi, Japanen_US
dc.identifier.affiliationMihara Memorial Hospital, Isesaki, Japanen_US
dc.identifier.affiliationAustin Health, University of Melbourne, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationThe Florey Institute, The University of Melbourne, Australiaen_US
dc.identifier.affiliationDepartment of Nuclear Medicine, Leipzig University, Leipzig, Germanyen_US
dc.identifier.affiliationDepartment of Psychiatry, Leipzig University, Leipzig, Germanyen_US
dc.identifier.affiliationDepartment of Psychiatry and Psychotherapy, Charité Berlin, Berlin, Germanyen_US
dc.identifier.affiliationDepartment of Psychiatry, Stanford School of Medicine, Stanford, USAen_US
dc.identifier.affiliationPiramal Imaging GmbH, Berlin, Germanyen_US
dc.identifier.affiliationGeorg-August University Göttingen, Göttingen, Germanyen_US
dc.identifier.affiliationMolecular Neuroimaging, New Haven, CT, USAen_US
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/27983552en_US
dc.identifier.doi10.3233/JAD-160821en_US
dc.type.contentTexten_US
dc.identifier.orcid0000-0003-3910-2453en_US
dc.type.austinJournal Articleen_US
local.name.researcherMasters, Colin L
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptMolecular Imaging and Therapy-
crisitem.author.deptThe Florey Institute of Neuroscience and Mental Health-
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