Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16369
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dc.contributor.authorOwen, Claire E-
dc.contributor.authorBuchanan, Russell R C-
dc.contributor.authorHoi, A-
dc.date.accessioned2016-10-18T03:07:45Z-
dc.date.available2016-10-18T03:07:45Z-
dc.date.issued2015-11-
dc.identifier.citationInternal Medicine Journal 2015; 45(11): 1102-1108en
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/16369-
dc.description.abstractPolymyalgia rheumatica (PMR) is a chronic inflammatory disorder of unknown cause characterised by the subacute onset of shoulder and pelvic girdle pain, and early morning stiffness in men and women over the age of 50 years. Due to the lack of a gold standard investigation, diagnosis is based on a clinical construct and laboratory evidence of inflammation. Heterogeneity in the clinical presentation and disease course of PMR has long been recognised. Aside from the evolution of alternative diagnoses, such as late-onset rheumatoid arthritis, concomitant giant cell arteritis is also recognised in 16-21% of cases. In 2012, revised classification criteria were released by the European League Against Rheumatism and American College of Rheumatology in order to identify a more homogeneous population upon which future studies could be based. In this article, we aim to provide an updated perspective on the pathogenesis and diagnosis of PMR, with particular focus on imaging modalities, such as ultrasound and whole body positron emission tomography/computed tomography, which have advanced our current understanding of this disease. Future treatment directions, based on recognition of the key cytokines involved in PMR, will also be explored.en
dc.subjectPolymyalgia rheumaticaen
dc.subjectPrednisoloneen
dc.subjectUltrasounden
dc.subjectWhole body positron emission tomography/computed tomographyen
dc.titleRecent advances in polymyalgia rheumaticaen
dc.typeJournal Articleen
dc.identifier.journaltitleInternal Medicine Journalen
dc.identifier.affiliationDepartment of Rheumatology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australiaen
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/26036315en
dc.identifier.doi10.1111/imj.12823en
dc.type.contentTexten
dc.type.austinJournal Articleen_US
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.grantfulltextnone-
crisitem.author.deptRheumatology-
crisitem.author.deptRheumatology-
crisitem.author.deptRheumatology-
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