Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16366
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dc.contributor.authorLee, Wei-I-
dc.contributor.authorAmeratunga, Malaka-
dc.contributor.authordu Plessis, Justin-
dc.contributor.authorGan, Hui K-
dc.date2015-12-29-
dc.date.accessioned2016-10-17T04:39:08Z-
dc.date.available2016-10-17T04:39:08Z-
dc.date.issued2015-12-29-
dc.identifier.citationBMJ Case Reports 2015; online first: 29 Decemberen_US
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/16366-
dc.description.abstractNeuroendocrine carcinoma (NEC) of the head and neck is rare. We report a case of a 56-year-old man with a 6-week history of dysphagia, a neck mass and weight loss. He was diagnosed with a hypopharyngeal large cell NEC (LCNEC) with metastases to multiple sites. He received two cycles of cisplatin and etoposide. Subsequent restaging scan revealed progressive disease. The patient declined further chemotherapy and died shortly after. This is the third case of LCNEC of hypopharynx reported in the English literature and the first to progress on platinum-based chemotherapy. Although LCNEC of the head and neck is still classified as an atypical carcinoid, there is increasing evidence it is a distinct clinicohistopathological entity that carries an especially poor prognosis. Currently, there is a paucity of data to guide treatment of this rare malignancy.en_US
dc.titleHypopharyngeal large cell neuroendocrine carcinomaen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleBMJ Case Reportsen_US
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Oncology, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Pathology, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/26715138en_US
dc.identifier.doi10.1136/bcr-2015-211908en_US
dc.type.contentTexten_US
dc.type.austinJournal Articleen_US
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
crisitem.author.deptMedical Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
Appears in Collections:Journal articles
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