Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16198
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dc.contributor.authorGleeson, Mary-
dc.contributor.authorHawkes, Eliza A-
dc.contributor.authorCunningham, David-
dc.contributor.authorChadwick, Nick-
dc.contributor.authorCounsell, Nicholas-
dc.contributor.authorLawrie, Anthony-
dc.contributor.authorJack, Andrew-
dc.contributor.authorSmith, Paul-
dc.contributor.authorMouncey, Paul-
dc.contributor.authorPocock, Christopher-
dc.contributor.authorArdeshna, Kirit M-
dc.contributor.authorRadford, John-
dc.contributor.authorMcMillan, Andrew-
dc.contributor.authorDavies, John-
dc.contributor.authorTurner, Deborah-
dc.contributor.authorKruger, Anton-
dc.contributor.authorJohnson, Peter WM-
dc.contributor.authorGambell, Joanna-
dc.contributor.authorLinch, David-
dc.date2016-08-01-
dc.date.accessioned2016-09-06T05:39:36Z-
dc.date.available2016-09-06T05:39:36Z-
dc.date.issued2016-08-01-
dc.identifier.citationBritish Journal of Haematology 2016; online first: 1 Augusten_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/16198-
dc.description.abstractWe performed a subgroup analysis of the phase III UK National Cancer Research Institute R-CHOP-14 versus R-CHOP-21 (two- versus three-weekly rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) trial to evaluate the outcomes for 50 patients with World Health Organization 2008 classified primary mediastinal B-cell lymphoma identified from the trial database. At a median follow-up of 7·2 years the 5-year progression-free survival and overall survival was 79·8% and 83·8%, respectively. An exploratory analysis raised the possibility of a better outcome in those who received R-CHOP-14 and time intensification may still, in the rituximab era, merit testing in a randomised trial in this subgroup of patients.en_US
dc.subjectLymphoma, Large B-Cell, Diffuseen_US
dc.subjectLymphoma, Non-Hodgkinen_US
dc.subjectLymphoma, B-Cellen_US
dc.subjectRituximaben_US
dc.subjectCyclophosphamideen_US
dc.subjectDoxorubicinen_US
dc.subjectVincristineen_US
dc.subjectPrednisoloneen_US
dc.titleRituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) in the management of primary mediastinal B-cell lymphoma: a subgroup analysis of the UK NCRI R-CHOP 14 versus 21 trialen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleBritish Journal of Haematologyen_US
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationThe Royal Marsden Hospital, London and Surrey, UKen_US
dc.identifier.affiliationDepartment of Oncology and Clinical Haematology, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationEastern Health, Melbourne, Victoria, Australiaen_US
dc.identifier.affiliationCancer Research UK and UCL Cancer Trials Centre, UCL Cancer Institute, London, UKen_US
dc.identifier.affiliationHMDS, Leeds Teaching Hospitals NHS Trust, Leeds, UKen_US
dc.identifier.affiliationEast Kent Hospitals, Canterbury, UKen_US
dc.identifier.affiliationUniversity College London, London, UKen_US
dc.identifier.affiliationMount Vernon Cancer Centre, Northwood, UKen_US
dc.identifier.affiliationThe University of Manchester and the Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UKen_US
dc.identifier.affiliationNottingham City Hospital, Nottingham, UKen_US
dc.identifier.affiliationWestern General Hospital, Edinburgh, UKen_US
dc.identifier.affiliationTorbay Hospital, Torquay, UKen_US
dc.identifier.affiliationRoyal Cornwall Hospital, Truro, UKen_US
dc.identifier.affiliationCancer Research UK Centre, Southampton, UKen_US
dc.type.studyortrialClinical Trialen_US
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/27477167en_US
dc.identifier.doi10.1111/bjh.14287en_US
dc.type.contentTexten_US
dc.type.austinJournal Articleen_US
local.name.researcherHawkes, Eliza A
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
crisitem.author.deptClinical Haematology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
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