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dc.contributor.authorJoosten, Simon A-
dc.contributor.authorO'Donoghue, Fergal J-
dc.contributor.authorRochford, Peter D-
dc.contributor.authorBarnes, Maree-
dc.contributor.authorHamza, Kais-
dc.contributor.authorChurchward, Thomas J-
dc.contributor.authorBerger, Philip J-
dc.contributor.authorHamilton, Garun S-
dc.identifier.citationAnnals of the American Thoracic Society 2014; 11(5): 761-769en_US
dc.description.abstractRATIONALE: Patients with obstructive sleep apnea (OSA) experience respiratory events with greater frequency and severity while in the supine sleeping position. Postural modification devices (PMDs) prevent supine sleep, although there is a paucity of guidance to help clinicians decide when to use PMDs for their patients. In order for PMDs to treat OSA effectively, patients must experience respiratory events in the supine sleeping position consistently from night to night and must have a low nonsupine apnea and hypopnea index (AHINS). OBJECTIVES: To document the repeatability of traditionally defined supine predominant OSA on consecutive polysomnography, to determine whether the consistency of the supine-predominant phenotype can be improved by altering the definition of it, and to determine whether a low AHINS is repeatable from night to night. METHODS: We recruited 75 patients for polysomnography on two separate nights. Patients were classified as having supine OSA on each night on the basis of traditional and novel definitions, and the classification systems used were compared on the basis of agreement from night to night. MEASUREMENTS AND MAIN RESULTS: The definition of supine OSA with the highest level of agreement from night to night incorporates a supine AHI (AHIS) to AHINS ratio ≥4:1. In addition, agreement exists for males, but there is poor agreement for female patients, regardless of the definition applied. An AHINS <10 events/hour is highly repeatable from night to night. CONCLUSIONS: Males with an AHIS:AHINS ratio ≥4:1 and an AHINS <10 events/hour represent a consistent supine-predominant OSA phenotype from night to night. This patient group is likely to benefit from treatment with PMD.en_US
dc.subjectSleep-disordered breathingen_US
dc.titleNight-to-night repeatability of supine-related obstructive sleep apneaen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleAnnals of the American Thoracic Societyen_US
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationMonash Lung and Sleep, Monash Health, Clayton, Victoriaen_US
dc.identifier.affiliationRitchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australiaen_US
dc.identifier.affiliationSchool of Mathematical Sciences, Monash University, Clayton, Victoria, Australiaen_US
dc.identifier.affiliationInstitute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.type.austinJournal Articleen_US, Maree
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.grantfulltextnone- and Sleep Medicine- for Breathing and Sleep- and Sleep Medicine- for Breathing and Sleep- for Breathing and Sleep- for Breathing and Sleep-
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