Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/13723
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dc.contributor.authorvan Silfhout, L-
dc.contributor.authorPeters, AE-
dc.contributor.authorBerlowitz, David J-
dc.contributor.authorSchembri, R-
dc.contributor.authorThijssen, D-
dc.contributor.authorGraco, Marnie-
dc.date2016-01-12-
dc.date.accessioned2016-01-20T09:45:13Z-
dc.date.accessioned2016-01-20T09:44:35Z-
dc.date.available2016-01-20T09:45:13Z-
dc.date.available2016-01-20T09:44:35Z-
dc.date.issued2016-01-12-
dc.identifier.citationSpinal Cord 2016; 54(9): 714-719en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/13723-
dc.description.abstractSTUDY DESIGN: Retrospective study. OBJECTIVES: To model the effect of time since injury on longitudinal respiratory function measures in spinal cord injured-individuals and to investigate the effect of patient characteristics. SETTING: A total of 173 people who sustained a spinal cord injury between 1966 and April 2013 and who had previously participated in research or who underwent clinically indicated outpatient respiratory function tests at the Austin Hospital in Melbourne, Australia, were included in the study. At least two measurements over time were available for analysis in 59 patients. METHODS: Longitudinal data analysis was performed using generalised linear regression models to determine changes in respiratory function following spinal cord injury from immediately post injury to many years later. Secondly, we explored whether injury severity, age, gender and body mass index (BMI) at injury altered the time-dependent change in respiratory function. RESULTS: The generalised linear regression model showed no significant change (P=0.276) in respiratory function measured in (forced) vital capacity ((F)VC) after the spinal cord injury. However, significant (P<0.05) differences in respiratory function over time were found when categorising age and BMI. CONCLUSION: This clinical cohort with long-term, repeated measurements of respiratory function showed no significant overall change in respiratory function over 23 years. However, a decline in respiratory function over time was observed in subgroups of individuals older than 30 years at the onset of injury and in those with a BMI>30 kg m-2en_US
dc.subjectSpinal Cord Injuriesen_US
dc.subjectRespirationen_US
dc.subjectLongitudinal Studiesen_US
dc.subjectRespiratory Function Testsen_US
dc.titleLong-term change in respiratory function following spinal cord injuryen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleSpinal Corden_US
dc.identifier.affiliationRadboud University Nijmegen Medical Centre. Department of Physiology, Nijmegen, The Netherlandsen_US
dc.identifier.affiliationInstitute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.type.studyortrialCohort Studyen_US
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/26754472en_US
dc.identifier.doi10.1038/sc.2015.233en_US
dc.type.contentTexten_US
dc.identifier.orcid0000-0003-2543-8722-
dc.type.austinJournal Articleen_US
local.name.researcherBerlowitz, David J
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeJournal Article-
crisitem.author.deptPhysiotherapy-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptInstitute for Breathing and Sleep-
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