Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/13396
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dc.contributor.authorBach, Leon Aen
dc.contributor.authorGilbert, Richard Een
dc.contributor.authorCooper, Mark Een
dc.contributor.authorTsalamandris, Conen
dc.contributor.authorJerums, Georgeen
dc.date.accessioned2015-05-16T03:14:21Z
dc.date.available2015-05-16T03:14:21Z
dc.date.issued1993-04-06en
dc.identifier.citationJournal of Diabetes and Its Complications; 7(2): 67-72en
dc.identifier.govdoc8518458en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/13396en
dc.description.abstractPersistent microalbuminuria [albumin excretion rate (AER): 30-300 micrograms/min] is predictive of clinical nephropathy in patients with insulin-dependent diabetes mellitus (IDDM) and cardiovascular mortality in addition to nephropathy in patients with non-insulin-dependent diabetes. The clinical significance of intermittent microalbuminuria, however, is unknown. We performed serial measurements of urinary albumin excretion at intervals of approximately 6 months in 139 diabetic patients who at entry did not have persistent microalbuminuria to determine whether intermittent microalbuminuria occurs more frequently in those patients who subsequently develop persistent microalbuminuria. The relative risk for the development of persistent microalbuminuria in diabetic patients with a greater proportion than 3 out of 20 determinations in the microalbuminuric range was 17.4 (95% confidence interval, 3.92-77.2) in those with IDDM and 2.78 (0.99-7.8) in those with non-insulin-dependent diabetes when compared with matched diabetic patients with fewer elevated measurements. These data suggest that frequent intermittent microalbuminuria predicts the future development of persistent microalbuminuria particularly in IDDM patients and that AER should be assessed by serial rather than single measurements.en
dc.language.isoenen
dc.subject.otherAdolescenten
dc.subject.otherAdulten
dc.subject.otherAlbuminuriaen
dc.subject.otherChilden
dc.subject.otherDiabetes Mellitus, Type 1.mortality.physiopathology.urineen
dc.subject.otherDiabetes Mellitus, Type 2.mortality.physiopathology.urineen
dc.subject.otherDiabetic Nephropathies.diagnosis.epidemiologyen
dc.subject.otherFollow-Up Studiesen
dc.subject.otherHumansen
dc.subject.otherMiddle Ageden
dc.subject.otherPrognosisen
dc.subject.otherRetrospective Studiesen
dc.subject.otherRisk Factorsen
dc.subject.otherSurvival Analysisen
dc.subject.otherTime Factorsen
dc.titlePrediction of persistent microalbuminuria in patients with diabetes mellitus.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of diabetes and its complicationsen
dc.identifier.affiliationEndocrinology Unit, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages67-72en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/8518458en
dc.type.austinJournal Articleen
local.name.researcherJerums, George
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptEndocrinology-
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