Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12829
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dc.contributor.authorMcIntyre, I Men
dc.contributor.authorNorman, Trevor Ren
dc.contributor.authorBurrows, Graham Den
dc.contributor.authorArmstrong, S Men
dc.date.accessioned2015-05-16T02:34:28Z
dc.date.available2015-05-16T02:34:28Z
dc.date.issued1989-05-16en
dc.identifier.citationLife Sciences; 45(4): 327-32en
dc.identifier.govdoc2761346en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12829en
dc.description.abstractPlasma melatonin concentrations were examined following three relatively low intensities of artificial light. Six normal, healthy control subjects were all exposed to (a) 200 lux, (b) 400 lux and (c) 600 lux for a three hour duration from midnight to 0300 h. Blood was also collected on a control night where light intensity was less than 10 lux throughout. Significant suppression of melatonin was observed following light of 400 lux and 600 lux intensity when compared to the control night (p less than 0.05; Mann-Whitney U-test). 200 lux light did not produce a statistically significant melatonin suppression when compared with control samples. Each light intensity produced its own individual maximal melatonin suppression by one hour of exposure. Increased duration of exposure to the light had no further influence on melatonin plasma concentrations. These data confirm a dose response relationship between light and melatonin suppression, and indicate that there is no reciprocal relationship between the effects of light intensity and the duration of exposure on maximal melatonin suppression in man.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherCircadian Rhythmen
dc.subject.otherHumansen
dc.subject.otherLighten
dc.subject.otherMelatonin.blood.secretionen
dc.subject.otherRadioimmunoassayen
dc.subject.otherReference Valuesen
dc.titleQuantal melatonin suppression by exposure to low intensity light in man.en
dc.typeJournal Articleen
dc.identifier.journaltitleLife sciencesen
dc.identifier.affiliationDepartment of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages327-32en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2761346en
dc.type.austinJournal Articleen
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptPsychiatry (University of Melbourne)-
Appears in Collections:Journal articles
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