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https://ahro.austin.org.au/austinjspui/handle/1/12738
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Wight, J | en |
dc.contributor.author | Morris, E | en |
dc.contributor.author | Stillwell, A | en |
dc.contributor.author | Grant, B | en |
dc.contributor.author | Lai, H C | en |
dc.contributor.author | Irving, I | en |
dc.date.accessioned | 2015-05-16T02:28:15Z | |
dc.date.available | 2015-05-16T02:28:15Z | |
dc.date.issued | 2015-04-14 | en |
dc.identifier.citation | Internal Medicine Journal; 45(7): 762-5 | en |
dc.identifier.govdoc | 25870934 | en |
dc.identifier.other | PUBMED | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/12738 | en |
dc.description.abstract | Magnetic Resonance Imaging (MRI) is the most sensitive method for detecting focal spinal disease (FSD) in multiple myeloma (MM). It is unclear whether whole spine MRI (WS-MRI) should be employed as a screening test at diagnosis of MM.To determine the utility of screening WS-MRI at diagnosis of MM.A retrospective analysis of data from January 2008 to January 2013 at The Townsville Hospital was performed. At this centre, WS-MRI is used routinely in all newly diagnosed MM. The findings of WS-MRI in patients with and without an agreed guideline indication for WS-MRI were compared. Clinical predictors of FSD were determined.71 patients were included in the analysis. 44 (62%) had an agreed indication for MRI; 33 (75%) of these had FSD. Within this group, 17 required urgent intervention and 13 had spinal plasmacytomas. Within a second group without a guideline indication, 4 of 27 (15%) were found to have FSD on MRI - none required urgent intervention and or had plasmacytomas. 3 of 8 smouldering myeloma patients were reclassified as symptomatic myeloma by documenting lytic lesions not identified on plain film. The strongest predictors of FSD were back pain (p<0.001) and vertebral compression fracture (p=0.003).WS-MRI in patients without a guideline indication did not detect any lesions that threatened the spinal cord. WS-MRI is essential in those with guideline indications. WS-MRI is of benefit to patients with smouldering myeloma where documentation of lesions not seen on plain film will result in treatment rather than observation. | en |
dc.language.iso | en | en |
dc.subject.other | MRI spine | en |
dc.subject.other | Multiple Myeloma | en |
dc.subject.other | Plasmacytoma | en |
dc.subject.other | Smouldering Myeloma | en |
dc.title | Screening whole spine Magnetic Resonance Imaging (MRI) in multiple myeloma. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | Internal Medicine Journal | en |
dc.identifier.affiliation | Austin health service, department of haematology; James Cook University, School of Medicine and Dentistry. | en |
dc.identifier.doi | 10.1111/imj.12789 | en |
dc.relation.url | https://pubmed.ncbi.nlm.nih.gov/25870934 | en |
dc.type.austin | Journal Article | en |
local.name.researcher | Wight, Joel C | |
item.grantfulltext | none | - |
item.openairetype | Journal Article | - |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Clinical Haematology | - |
crisitem.author.dept | Olivia Newton-John Cancer Wellness and Research Centre | - |
Appears in Collections: | Journal articles |
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