Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/12554
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Le Bas, James | en |
dc.contributor.author | Newton, Richard | en |
dc.contributor.author | Sore, Rachel | en |
dc.contributor.author | Castle, David J | en |
dc.date.accessioned | 2015-05-16T02:16:02Z | |
dc.date.available | 2015-05-16T02:16:02Z | |
dc.date.issued | 2014-12-15 | en |
dc.identifier.citation | Medical Hypotheses 2014; 84(2): 122-8 | en |
dc.identifier.govdoc | 25554538 | en |
dc.identifier.other | PUBMED | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/12554 | en |
dc.description.abstract | Because affective pathogenesis is a hard problem for psychiatry, it behoves researchers to develop and test novel models of causality. We examine the notion that the adaptive drive to social investment - prestige - provides clues to the bipolar spectrum. A seven node bipolar spectrum is proposed, based on a putative gradient of "bipolarity". It is conceived that this gradient may correlate with the drive to social investment (prestige). In order to test this hypothesis with proof of concept data, a case control study categorised 228 subjects into a seven node bipolar spectrum. Whilst controlling for mood elevation and depression, differences in strategic prestige (leadership) motivation (MSPM) between spectrum groups were examined. The bipolar I (S1) node had a greater strategic prestige (leadership) motivation score than the controls (S7) by 21.17 points, 95% CI [8.16, 34.18], p<.001, d=1.05, while the bipolar II (S2) node was higher than the control group by 16.73 points, 95% CI [0.92, 32.54], p=.030, d=0.84. Whilst the pseudounipolar (S3) node (those with depression and bipolar family histories; n=17) had only a marginally statistical difference in MSPM compared to controls (p=.051), the mean difference (16.98) and d value (0.86) indicated an elevated MSPM level. Prestige (leadership) motivation score positively correlated with dimensional lifetime bipolarity (Mood Disorder Questionnaire) score (rp=0.47), supporting the spectrum prestige motivation gradient notion. Evidence is presented for a genetic disposition to elevated strategic prestige (leadership) motivation. Sensitivity to Social Inclusion (MSIS), Contingency of Self-Worth (CSW.av) and tension significantly predicted strategic prestige (leadership) motivation (MSPM) score in a multiple regression. - suggesting that a vulnerability of the social self may be a feature of bipolar disorders. The prestige model of spectrum bipolarity offers a new conceptualisation of affective disorders and has received preliminary support. | en |
dc.language.iso | en | en |
dc.title | The prestige model of spectrum bipolarity. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | Medical hypotheses | en |
dc.identifier.affiliation | The University of Melbourne, Melbourne, Australia | en |
dc.identifier.affiliation | Peninsula Health, Melbourne, Australia | en |
dc.identifier.affiliation | Monash University, Melbourne, Australia | en |
dc.identifier.affiliation | Statistical Consulting Centre, University of Melbourne, Australia | en |
dc.identifier.affiliation | St Vincent's Health, Melbourne, Australia | en |
dc.identifier.affiliation | Austin Health, Melbourne, Australia | en |
dc.identifier.doi | 10.1016/j.mehy.2014.12.005 | en |
dc.description.pages | 122-8 | en |
dc.relation.url | https://pubmed.ncbi.nlm.nih.gov/25554538 | en |
dc.type.austin | Journal Article | en |
item.openairetype | Journal Article | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
Appears in Collections: | Journal articles |
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.