Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12468
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dc.contributor.authorGoh, M Yen
dc.contributor.authorWong, E C Ken
dc.contributor.authorMillard, M Sen
dc.contributor.authorBrown, Douglas Jen
dc.contributor.authorO'Callaghan, Christopher Jen
dc.date.accessioned2015-05-16T02:10:13Z
dc.date.available2015-05-16T02:10:13Z
dc.date.issued2014-11-11en
dc.identifier.citationSpinal Cord 2014; 53(1): 49-53en
dc.identifier.govdoc25384400en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12468en
dc.description.abstractRetrospective study.To quantify diurnal blood pressure (BP) patterns and nocturnal hypertension and to measure diurnal urine production in spinal cord injury (SCI) patients with clinically significant disorders of BP control.A specialist state-based spinal cord service in Victoria, Australia.Medical records of patients with traumatic SCI who were referred to a specialist service for management of a BP disorder were examined. Ambulatory BP and nocturnal urine production were compared between groups of patients classified according to level, completeness and chronicity of SCI. Patients with night:day systolic BP <90% were classified as dippers, 90-100% as non-dippers and >100% as reversed dippers.Patients (44 tetraplegic, 10 paraplegic) were predominantly males (92.6%) aged 41±2.5 years (mean±s.e.m.). Referral was for orthostatic intolerance (n=37), autonomic dysreflexia (n=6), nocturnal polyuria (n=4), elevated BP (n=1) and peripheral oedema (n=1). The average BP was 111.1±1.4/65.0±1.2 mm Hg. In 56% of patients (n=30), BP at night was higher than during the day and another 37% (n=20) were non-dippers. Nocturnal hypertension was present in 31% (n=17) of the patients. In the tetraplegic patients, urine flow rate was greater during the night than day (121±9.5 ml h(-1) vs 89±8.2 ml h(-1), P=0.025).Ambulatory BP monitoring in patients with SCI and clinically significant BP disorders detected a high incidence of reversed dipping and nocturnal hypertension. We postulate elevated nocturnal BP may contribute to nocturnal diuresis that might cause relative volume depletion and thereby contribute to daytime orthostatic hypotension.en
dc.language.isoenen
dc.titleA retrospective review of the ambulatory blood pressure patterns and diurnal urine production in subgroups of spinal cord injured patients.en
dc.typeJournal Articleen
dc.identifier.journaltitleSpinal Corden
dc.identifier.affiliationThe Spinal Research Institute, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Clinical Pharmacology, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationThe Spinal Research Institute, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationVictorian Spinal Cord Service, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Clinical Pharmacology, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationUniversity of Melbourne, Parkville, Victoria, Australiaen
dc.identifier.doi10.1038/sc.2014.192en
dc.description.pages49-53en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/25384400en
dc.type.austinJournal Articleen
local.name.researcherO'Callaghan, Christopher J
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.deptClinical Pharmacology and Therapeutics-
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