Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12409
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dc.contributor.authorCooper, Mark Een
dc.contributor.authorO'Brien, R Cen
dc.contributor.authorMurray, R Men
dc.contributor.authorSeeman, Egoen
dc.contributor.authorJerums, Georgeen
dc.date.accessioned2015-05-16T02:06:18Z
dc.date.available2015-05-16T02:06:18Z
dc.date.issued1989-04-06en
dc.identifier.citationThe Journal of Diabetic Complications; 3(2): 92-8en
dc.identifier.govdoc2526146en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12409en
dc.description.abstractThe factors associated with intermittent microalbuminuria were studied over 7 years in 49 Type I and 53 Type II diabetics who had normal initial albumin clearance. Fasting plasma glucose, HbA1, 24 hour urinary glucose, blood pressure, protein intake (24 hour urinary urea), and the renal clearance of albumin, transferrin, and IgG, as well as total proteinuria, were assessed every 3-6 months. Fifteen Type I and 11 Type II diabetics had 40 and 31 episodes, respectively, of intermittent microalbuminuria, defined as an albumin clearance greater than 11 nl/sec, without progressing to persistent microalbuminuria. Rises in transferrin and IgG clearance paralleled albumin clearance in both Type I and Type II diabetics. There were no significant changes in blood pressure or glycemic control during episodes of intermittent microalbuminuria. However, in Type I diabetics, intermittent microalbuminuria was associated with higher levels of urinary urea excretion. This study raises the possibility that increased protein intake may participate in the development of nephropathy in Type I diabetes.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherAlbuminuriaen
dc.subject.otherBlood Glucose.metabolismen
dc.subject.otherBlood Pressureen
dc.subject.otherCohort Studiesen
dc.subject.otherDiabetes Mellitus, Type 1.blood.physiopathology.urineen
dc.subject.otherDiabetes Mellitus, Type 2.blood.physiopathology.urineen
dc.subject.otherDietary Proteinsen
dc.subject.otherFemaleen
dc.subject.otherFollow-Up Studiesen
dc.subject.otherGlycosuriaen
dc.subject.otherHemoglobin A, Glycosylated.analysisen
dc.subject.otherHumansen
dc.subject.otherImmunoglobulin G.urineen
dc.subject.otherKidney.physiopathologyen
dc.subject.otherMaleen
dc.subject.otherTransferrin.urineen
dc.titleIntermittent diabetic microalbuminuria: association with blood pressure, glycemic control, and protein intake.en
dc.typeJournal Articleen
dc.identifier.journaltitleThe Journal of diabetic complicationsen
dc.identifier.affiliationDepartment of Medicine, Austin Hospital, University of Melbourne, Victoria, Australiaen
dc.description.pages92-8en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2526146en
dc.type.austinJournal Articleen
local.name.researcherJerums, George
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
crisitem.author.deptEndocrinology-
crisitem.author.deptEndocrinology-
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