Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12316
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dc.contributor.authorWorth, Leon Jen
dc.contributor.authorSlavin, M Aen
dc.contributor.authorHeath, Sen
dc.contributor.authorSzer, Jen
dc.contributor.authorGrigg, Andrew Pen
dc.date.accessioned2015-05-16T01:58:51Z-
dc.date.available2015-05-16T01:58:51Z-
dc.date.issued2014-07-02en
dc.identifier.citationThe Journal of Hospital Infection 2014; 88(1): 48-51en
dc.identifier.govdoc25063013en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12316en
dc.description.abstractThe effectiveness of ethanol locks for prevention of central venous catheter (CVC)-associated bloodstream infection (CLABSI) in adult haematology patients has not been thoroughly evaluated. This study aimed to compare prospectively heparinized saline with 70% ethanol locks using 2 h dwell time in patients with tunnelled CVCs. In saline (N = 43) and ethanol (N = 42) groups, CLABSI rates were 6.0 [95% confidence interval (CI): 3.4-9.8] and 4.1 (95% CI: 1.9-7.7) per 1000 CVC days, respectively (P = 0.42). In the ethanol group, two exit-site infections and one tunnel/pocket infection were observed. Reduction in device-associated infection was not achieved with prophylactic 70% ethanol locks in patients with haematological malignancy and tunnelled CVCs.en
dc.language.isoenen
dc.subject.otherBloodstream infectionen
dc.subject.otherBone marrow transplantationen
dc.subject.otherCentral venous catheteren
dc.subject.otherEthanol locken
dc.subject.otherHaematologyen
dc.subject.otherProphylaxisen
dc.subject.otherAdolescenten
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherAnticoagulants.pharmacologyen
dc.subject.otherCatheter-Related Infections.prevention & controlen
dc.subject.otherCentral Venous Catheters.microbiologyen
dc.subject.otherDisinfectants.pharmacologyen
dc.subject.otherEthanol.pharmacologyen
dc.subject.otherFemaleen
dc.subject.otherHematologic Neoplasms.complicationsen
dc.subject.otherHeparin.pharmacologyen
dc.subject.otherHumansen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherProspective Studiesen
dc.subject.otherSepsis.prevention & controlen
dc.subject.otherTreatment Outcomeen
dc.subject.otherYoung Adulten
dc.titleEthanol versus heparin locks for the prevention of central venous catheter-associated bloodstream infections: a randomized trial in adult haematology patients with Hickman devices.en
dc.typeJournal Articleen
dc.identifier.journaltitleThe Journal of hospital infectionen
dc.identifier.affiliationVictorian Infectious Diseases Service, The Royal Melbourne Hospital, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Haematology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Clinical Haematology and Bone Marrow Transplant Service, The Royal Melbourne Hospital and University of Melbourne, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Infectious Diseases and Infection Prevention, Peter MacCallum Cancer Centre, Australiaen
dc.identifier.doi10.1016/j.jhin.2014.06.007en
dc.description.pages48-51en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/25063013en
dc.type.austinJournal Articleen
local.name.researcherGrigg, Andrew P
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptClinical Haematology-
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