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dc.contributor.authorAtanasova, Iliyana Pen
dc.contributor.authorLim, Ruth Pen
dc.contributor.authorChandarana, Hershen
dc.contributor.authorStorey, Pippaen
dc.contributor.authorBruno, Mary Ten
dc.contributor.authorKim, Danielen
dc.contributor.authorLee, Vivian Sen
dc.identifier.citationEuropean Journal of Radiology 2014; 83(9): 1612-9en
dc.description.abstractThe purpose of this study is to assess the image quality and diagnostic accuracy of non-contrast quadruple inversion-recovery balanced-SSFP MRA (QIR MRA) for detection of aortoiliac disease in a clinical population. QIR MRA was performed in 26 patients referred for routine clinical gadolinium-enhanced MRA (Gd-MRA) for known or suspected aortoiliac disease. Non-contrast images were independently evaluated for image quality and degree of stenosis by two radiologists, using consensus Gd-MRA as the reference standard. Hemodynamically significant stenosis (≥50%) was found in 10% (22/226) of all evaluable segments on Gd-MRA. The sensitivity and specificity for stenosis evaluation by QIR MRA for the two readers were 86%/86% and 95%/93% respectively. Negative predictive value and positive predictive value were 98%/98% and 63%/53% respectively. For stenosis evaluation of the aortoiliac region QIR MRA showed good agreement with the reference standard with high negative predictive value and a tendency to overestimate mild disease presumably due to the flow-dependence of the technique. QIR MRA could be a reasonable alternative to Gd-MRA for ruling out stenosis when contrast is contraindicated due to impaired kidney function or in patients who undergo abdominal MRA for screening purposes. Further work is necessary to improve performance and justify routine clinical use.en
dc.subject.otherAged, 80 and overen
dc.subject.otherAorta, Abdominal.pathologyen
dc.subject.otherAortic Diseases.diagnosisen
dc.subject.otherConstriction, Pathologic.diagnosisen
dc.subject.otherContrast Media.diagnostic useen
dc.subject.otherGadolinium.diagnostic useen
dc.subject.otherIliac Artery.pathologyen
dc.subject.otherImage Enhancement.methodsen
dc.subject.otherImage Processing, Computer-Assisted.methodsen
dc.subject.otherMagnetic Resonance Angiography.methodsen
dc.subject.otherMiddle Ageden
dc.subject.otherObserver Variationen
dc.subject.otherPredictive Value of Testsen
dc.subject.otherReproducibility of Resultsen
dc.titleQuadruple inversion-recovery b-SSFP MRA of the abdomen: initial clinical validation.en
dc.typeJournal Articleen
dc.identifier.journaltitleEuropean journal of radiologyen
dc.identifier.affiliationUniversity of Melbourne, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Radiology, Austin Health, Heidelberg, Victoria 3084, Australiaen
dc.identifier.affiliationDepartment of Radiology, New York University School of Medicine and Department of Biomedical Engineering, Columbia University, United Statesen
dc.identifier.affiliationDepartment of Radiology, New York University School of Medicine, 660 First Avenue, New York, NY 10016, United Statesen
dc.identifier.affiliationUtah Center for Advanced Imaging Research, Department of Radiology, University of Utah, United Statesen
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
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