Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12255
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dc.contributor.authorHuang, Gene Khai Lin-
dc.contributor.authorJohnson, Paul D R-
dc.date.accessioned2015-05-16T01:54:54Z
dc.date.available2015-05-16T01:54:54Z
dc.date.issued2014-07-01-
dc.identifier.citationExpert Review of Anti-infective Therapy; 12(7): 855-65en_US
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12255en
dc.description.abstractBuruli ulcer (Mycobacterium ulcerans infection) is a neglected tropical disease of skin and subcutaneous tissue that can result in long-term cosmetic and functional disability. It is a geographically restricted infection but transmission has been reported in endemic areas in more than 30 countries worldwide. The heaviest burden of disease lies in West and Sub-Saharan Africa where it affects children and adults in subsistence agricultural communities. Mycobacterium ulcerans infection is probably acquired via inoculation of the skin either directly from the environment or indirectly via insect bites. The environmental reservoir and exact route of transmission are not completely understood. It may be that the mode of acquisition varies in different parts of the world. Because of this uncertainty it has been nicknamed the 'mysterious disease'. The therapeutic approach has evolved in the past decade from aggressive surgical resection alone, to a greater focus on antibiotic therapy combined with adjunctive surgery.en_US
dc.language.isoenen
dc.subject.otherBuruli ulceren
dc.subject.otherInsertion sequence IS2404en
dc.subject.otherMycobacterium ulceransen
dc.subject.otherWHO neglected tropical diseaseen
dc.subject.otherclarithromycinen
dc.subject.otherfluroquinolonesen
dc.subject.othermycolactoneen
dc.subject.otherparadoxical reactionen
dc.subject.otherrifampicinen
dc.subject.otherstreptomycinen
dc.subject.otherAnimalsen
dc.subject.otherAnti-Bacterial Agents.adverse effects.therapeutic useen
dc.subject.otherBuruli Ulcer.epidemiology.pathology.therapy.transmissionen
dc.subject.otherDisease Reservoirs.microbiologyen
dc.subject.otherHumansen
dc.subject.otherNeglected Diseases.epidemiology.microbiology.pathology.therapyen
dc.subject.otherPrevalenceen
dc.subject.otherZoonoses.epidemiology.pathology.therapy.transmissionen
dc.titleEpidemiology and management of Buruli ulcer.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleExpert Review of Anti-infective Therapyen_US
dc.identifier.affiliationInfectiousen_US
dc.identifier.doi10.1586/14787210.2014.910113en_US
dc.description.pages855-65en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24918117en
dc.type.contentTexten_US
dc.type.austinJournal Articleen
local.name.researcherJohnson, Paul D R
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptInfectious Diseases-
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