Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12196
Full metadata record
DC FieldValueLanguage
dc.contributor.authorRose, Hannah Len
dc.contributor.authorHo, Wai Khoonen
dc.date.accessioned2015-05-16T01:51:04Z
dc.date.available2015-05-16T01:51:04Z
dc.date.issued2014-11-01en
dc.identifier.citationJournal of Thrombosis and Thrombolysis; 38(4): 453-6en
dc.identifier.govdoc24777280en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12196en
dc.description.abstractThere is a significantly increased risk of pregnancy complications in women with anti-phospholipid syndrome (APS). The risk is further heightened in those with previous arterial or venous thromboembolism and so-called 'triple positivity' for anti-phospholipid antibodies (i.e., when lupus anticoagulant, and anti-cardiolipin (aCL) and anti-β2 glycoprotein-I (anti-β2Gp-I) antibodies are all detected). Management of these cases is extremely difficult and little is available in the medical literature to guide therapy. This report describes the use of regular plasma exchanges (PEx) to bring about a successful pregnancy outcome in a woman with secondary APS and previous recurrent miscarriages. The patient was also anticoagulated with enoxaparin and administered aspirin, prednisolone, azathioprine and hydroxychloroquine. Through regular PEx and immunomodulation therapy, levels of aCL and anti-β2Gp-I antibodies were monitored and documented to fall as pregnancy progressed. Although the outcome in this case was successful, further experience is required before this regimen can be accepted as the standard of care for these patients at very high risk of pregnancy loss.en
dc.language.isoenen
dc.titleManagement of very high risk pregnancy with secondary anti-phospholipid syndrome and triple positivity to the anti-phospholipid antibodies.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of thrombosis and thrombolysisen
dc.identifier.affiliationDepartment of Haematology, Austin Health, Studley Road, Heidelberg, VIC, 3084, Australiaen
dc.identifier.doi10.1007/s11239-014-1080-7en
dc.description.pages453-6en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24777280en
dc.type.austinJournal Articleen
local.name.researcherHo, Wai Khoon
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.deptPathology-
crisitem.author.deptLaboratory Haematology-
Appears in Collections:Journal articles
Files in This Item:
File SizeFormat 
24777280.pdf43.77 kBAdobe PDFView/Open
Show simple item record

Page view(s)

8
checked on Mar 27, 2024

Download(s)

70
checked on Mar 27, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.