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Title: Clinical outcomes after arteriovenous fistula creation in chronic kidney disease.
Austin Authors: Lee, Mardiana ;Roberts, Matthew A;Smith, Maree-Ross;Chuen, Jason ;Mount, Peter F 
Affiliation: Nephrology
Issue Date: 26-Apr-2014
Publication information: Blood Purification 2014
Abstract: Optimal timing of arteriovenous fistula (AVF) surgery in chronic kidney disease (CKD) is uncertain.A single-centre retrospective study of pre-dialysis CKD patients having first AVF surgery.The median estimated glomerular filtration rate (eGFR) at the time of AVF surgery in 100 patients was 15 ml/min/1.73 m(2), with patients classified as having an early AVF if eGFR was >15 ml/min/1.73 m(2) (n = 46) or a late AVF if eGFR was ≤15 ml/min/1.73 m(2) (n = 54). In the eGFR ≤15 group, 81% of patients started haemodialysis (HD), compared with 63% of the eGFR >15 patients (p = 0.04). The median time to starting HD was 30.3 months in the eGFR >15 group compared to 10.7 months for the eGFR ≤15 group (log rank p = 0.018). There were no differences in the requirements for a dialysis catheter (eGFR >15 24% vs. eGFR ≤15 11%, p = 0.20) or additional access procedures between the two groups.AVF surgery with an eGFR >15 ml/min/1.73 m(2) was associated with a higher risk of AVF non-use and a more prolonged time to the need for HD.
DOI: 10.1159/000360273
Journal: Blood Purification
Type: Journal Article
Subjects: Aged
Arteriovenous Shunt, Surgical.methods
Follow-Up Studies
Middle Aged
Renal Dialysis
Renal Insufficiency, Chronic.therapy
Retrospective Studies
Time Factors
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