Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12155
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dc.contributor.authorChang, Joe H-
dc.contributor.authorLim Joon, Daryl-
dc.contributor.authorNguyen, Brandon T-
dc.contributor.authorHiew, Chee-Yan-
dc.contributor.authorEsler, Stephen-
dc.contributor.authorAngus, David-
dc.contributor.authorChao, Michael-
dc.contributor.authorWada, Morikatsu-
dc.contributor.authorQuong, George-
dc.contributor.authorKhoo, Vincent-
dc.date.accessioned2015-05-16T01:48:22Z
dc.date.available2015-05-16T01:48:22Z
dc.date.issued2013-08-29-
dc.identifier.citationJournal of Medical Imaging and Radiation Oncology 2013; 58(2): 237-43en_US
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12155en
dc.description.abstractConventional clinical staging for prostate cancer has many limitations. This study evaluates the impact of adding MRI scans to conventional clinical staging for guiding decisions about radiotherapy target coverage.This was a retrospective review of 115 patients who were treated between February 2002 and September 2005 with radical radiotherapy for prostate cancer. All patients had MRI scans approximately 2 weeks before the initiation of radiotherapy. The T stage was assessed by both conventional clinical methods (cT-staging) as well as by MRI (mT-staging). The radiotherapy target volumes were determined first based on cT-staging and then taking the additional mT staging into account. The number of times extracapsular extension or seminal vesicle invasion was incorporated into target volumes was quantified based on both cT-staging and the additional mT-staging.Extracapsular extension was incorporated into target volumes significantly more often with the addition of mT-staging (46 patients (40%) ) compared with cT-staging alone (37 patients (32%) ) (P = 0.002). Seminal vesicle invasion was incorporated into target volumes significantly more often with the addition of mT-staging (21 patients (18%) ) compared with cT-staging alone (three patients (3%) ) (P < 0.001). A total of 23 patients (20%) had changes to their target coverage based on the mT-staging.MRI scans can significantly change decisions about target coverage in radical radiotherapy for prostate cancer.en_US
dc.language.isoenen
dc.subject.othermagnetic resonance imagingen
dc.subject.otherprostate canceren
dc.subject.otherradiotherapyen
dc.subject.othertarget volume delineationen
dc.subject.otherAgeden
dc.subject.otherAged, 80 and overen
dc.subject.otherAlgorithmsen
dc.subject.otherHumansen
dc.subject.otherImage Interpretation, Computer-Assisted.methodsen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherNeoplasm Stagingen
dc.subject.otherProstatic Neoplasms.pathology.radiotherapyen
dc.subject.otherRadiotherapy Dosageen
dc.subject.otherRadiotherapy, Image-Guided.methodsen
dc.subject.otherReproducibility of Resultsen
dc.subject.otherRetrospective Studiesen
dc.subject.otherSensitivity and Specificityen
dc.subject.otherTreatment Outcomeen
dc.titleMRI scans significantly change target coverage decisions in radical radiotherapy for prostate cancer.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleJournal of Medical Imaging and Radiation Oncologyen_US
dc.identifier.affiliationDivision of Radiation Oncology and Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australiaen_US
dc.identifier.affiliationRadiation Oncologyen_US
dc.identifier.affiliationUniversity of Melbourne, Melbourne, Victoria, Australiaen_US
dc.identifier.doi10.1111/1754-9485.12107en_US
dc.description.pages237-43en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24690247en
dc.type.contentTexten_US
dc.type.austinJournal Articleen
local.name.researcherChao, Michael
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
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