Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12143
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dc.contributor.authorSood, Siddharthen
dc.contributor.authorTestro, Adam Gen
dc.date.accessioned2015-05-16T01:47:37Z
dc.date.available2015-05-16T01:47:37Z
dc.date.issued2014-03-24en
dc.identifier.citationWorld Journal of Transplantation; 4(1): 30-9en
dc.identifier.govdoc24669365en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12143en
dc.description.abstractMany of the causes of short and late morbidity following liver transplantation are associated with immunosuppression or immunosuppressive medications. Current care often involves close monitoring of liver biochemistry as well as therapeutic drug levels. However, the postoperative course following liver transplantation can often be associated with significant complications including infection and rejection, suggesting an inadequacy in current immune function monitoring. Many assays have been tested in the research setting to identify possible biomarkers that may be used to predict clinical events such as acute cellular rejection, and therefore allow modification of a patient's immunosuppressive regimen prior to a clinical event. However, these generally require significant laboratory processing and have had difficulty becoming established in common clinical use outside the research setting. One assay, Cylex ImmuKnow has been food and drug administration approved but has had variable results. In this review we discuss the assays that have been used to assess monitoring of immune function after liver transplantation and consider possible future directions.en
dc.language.isoenen
dc.subject.otherBiomarkersen
dc.subject.otherImmune function monitoringen
dc.subject.otherLiver transplantationen
dc.subject.otherReviewen
dc.titleImmune monitoring post liver transplant.en
dc.typeJournal Articleen
dc.identifier.journaltitleWorld journal of transplantationen
dc.identifier.affiliationSiddharth Sood, Adam G Testro, Liver Transplant Unit Victoria, Level 8 HSB, Austin Health, University of Melbourne, Melbourne, Victoria 3084, Australiaen
dc.identifier.doi10.5500/wjt.v4.i1.30en
dc.description.pages30-9en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24669365en
dc.type.austinJournal Articleen
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