Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12136
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dc.contributor.authorAsrar Ul Haq, Muhammad-
dc.contributor.authorWong, Chiew-
dc.contributor.authorLevinger, Itamar-
dc.contributor.authorSrivastava, Piyush M-
dc.contributor.authorSbaraglia, Melissa-
dc.contributor.authorToia, Deidre-
dc.contributor.authorJerums, George-
dc.contributor.authorSelig, Steve-
dc.contributor.authorHare, David L-
dc.date.accessioned2015-05-16T01:47:10Z
dc.date.available2015-05-16T01:47:10Z
dc.date.issued2014-03-10en
dc.identifier.citationClinical Medicine Insights. Cardiology 2014; 8(): 23-8en
dc.identifier.govdoc24653649en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12136en
dc.description.abstractThis study will examine the effects of combined aerobic and resistance training on left ventricular remodeling in diabetic patients with diastolic dysfunction. This is the first randomized controlled trial to look for effects of combined strength training and aerobic exercise on myocardial function as well as other clinical, functional, or psychological parameters in diabetic patients with isolated diastolic dysfunction, and will provide important insights into the potential management strategies for heart failure with preserved ejection fraction.This is a prospective, randomized controlled investigator initiated single center trial. Diabetic patients with LV diastolic dysfunction suitable for exercise training intervention will be randomized to three months of a supervised combination of aerobic and strength training exercises, or supervised light stretching (control arm). Pre and post intervention assessment will include stress echocardiography, peak aerobic power with 12-lead ECG, dual-energy X-ray absorptiometry, muscle strength, the capacity to perform activities of daily living (ADLs), and questionnaires to assess self-perceived quality of life and symptoms of depression. The primary endpoint is to compare any change in tissue Doppler-derived LV systolic and early diastolic velocities.The current trial protocol has been approved by the Human Research Ethics Committee of Austin Health and the University of Melbourne, Melbourne. The study will be performed in accordance with the Declaration of Helsinki. The investigator, regardless of the outcome, will publish the results of the study.ACTRN12610000943044.en
dc.language.isoenen
dc.subject.othercardiomyopathyen
dc.subject.otherechocardiographyen
dc.subject.otherheart failureen
dc.titleEffect of exercise training on left ventricular remodeling in diabetic patients with diastolic dysfunction: rationale and design.en
dc.typeJournal Articleen
dc.identifier.journaltitleClinical Medicine Insights. Cardiologyen
dc.identifier.affiliationDepartment of Cardiology, The Northern Hospital, Melbourne, Australiaen
dc.identifier.affiliation; Western Health, Melbourne, Australiaen
dc.identifier.affiliation; Department of Medicine, University of Melbourne, Melbourne, Australiaen
dc.identifier.affiliation; Austin Health, Melbourne, Australiaen
dc.identifier.affiliationDeakin University, Melbourne, Australiaen
dc.identifier.affiliationAustin Health, Melbourne, Australiaen
dc.identifier.affiliationInstitute for Sport, Exercise and Active Living (ISEAL), College of Sport and Exercise Science, Victoria University, Melbourne, Australiaen
dc.identifier.doi10.4137/CMC.S14089en
dc.description.pages23-8en
dc.identifier.orcid0000-0001-9554-6556-
dc.identifier.pubmedid24653649-
dc.type.austinJournal Articleen
local.name.researcherHare, David L
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptCardiology-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptCardiology-
crisitem.author.deptEndocrinology-
crisitem.author.deptCardiology-
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