Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11832
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dc.contributor.authorMcDonald, Christine Fen
dc.contributor.authorKhor, Yet Hen
dc.date.accessioned2015-05-16T01:27:40Z-
dc.date.available2015-05-16T01:27:40Z-
dc.date.issued2013-08-01en
dc.identifier.citationInternal Medicine Journal; 43(8): 854-862en
dc.identifier.govdoc23919334en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11832en
dc.description.abstractChronic obstructive pulmonary disease (COPD) is characterised by progressive airflow limitation in the presence of identifiable risk factors. Inflammation is the central pathological feature in the pathogenesis of COPD. In addition to its pulmonary effects, COPD is associated with significant extrapulmonary manifestations, including ischaemic heart disease, osteoporosis, stroke and diabetes. Anxiety and depression are also common. Spirometry remains the gold standard diagnostic tool. Pharmacologic and non-pharmacologic therapy can improve symptoms, quality of life and exercise capacity and, through their effects on reducing exacerbations, have the potential to modify disease progression. Bronchodilators are the mainstay of pharmacotherapy, with guidelines recommending a stepwise escalating approach. Smoking cessation is paramount in managing COPD, with promotion of physical activity and pulmonary rehabilitation being other key factors in management. Comorbidities should be actively sought and managed in their own right. Given the chronicity and progressive nature of COPD, ongoing monitoring and support with timely discussion of advanced-care planning and end-of-life issues are recommended.en
dc.language.isoenen
dc.subject.otherCOPDen
dc.subject.otherchronicen
dc.subject.otherchronic obstructive pulmonary diseaseen
dc.subject.otherlung diseaseen
dc.subject.otherupdateen
dc.subject.otherAnimalsen
dc.subject.otherBronchodilator Agents.administration & dosageen
dc.subject.otherHumansen
dc.subject.otherOxygen Inhalation Therapy.methodsen
dc.subject.otherPalliative Care.methodsen
dc.subject.otherPulmonary Disease, Chronic Obstructive.diagnosis.prevention & control.therapyen
dc.subject.otherRisk Factorsen
dc.subject.otherSmoking Cessation.methodsen
dc.subject.otherSpirometry.methodsen
dc.titleAdvances in chronic obstructive pulmonary disease.en
dc.typeJournal Articleen
dc.identifier.journaltitleInternal Medicine Journalen
dc.identifier.affiliationDepartment of Respiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1111/imj.12219en
dc.description.pages854-62en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/23919334en
dc.identifier.orcid0000-0002-5434-9342-
dc.identifier.orcid0000-0001-6481-3391-
dc.type.austinJournal Articleen
local.name.researcherKhor, Yet H
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptRespiratory and Sleep Medicine-
crisitem.author.deptRespiratory and Sleep Medicine-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptMedicine (University of Melbourne)-
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