Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11459
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dc.contributor.authorKwong, Jason C-
dc.contributor.authorChua, Kyra Y L-
dc.contributor.authorCharles, Patrick G P-
dc.date.accessioned2015-05-16T01:04:14Z
dc.date.available2015-05-16T01:04:14Z
dc.date.issued2012-06-01-
dc.identifier.citationCurrent Infectious Disease Reports; 14(3): 330-8en_US
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11459en
dc.description.abstractCommunity-associated methicillin-resistant Staphylococcus aureus (MRSA) is a rare, but significant cause of community-acquired pneumonia (CAP). A number of virulence determinants have been implicated in the development of severe community MRSA pneumonia, characterized by multilobar cavitating necrosis in patients without usual risk-factors for pneumonia. Optimal management is uncertain, and is extrapolated from anecdotal experiences with small case series, randomized studies of hospital-acquired pneumonia, and laboratory investigations using in vitro experiments and animal models of MRSA pneumonia. Adequate clinical suspicion, early diagnosis and administration of appropriate antibiotics are necessary for best patient outcomes, although some patients will still do badly even with early anti-MRSA therapy. Vancomycin or linezolid have been recommended as first-line therapy, possibly in combination with other antibiotics. Newer antibiotics such as ceftaroline are still being evaluated.en_US
dc.language.isoenen
dc.titleManaging Severe Community-Acquired Pneumonia Due to Community Methicillin-Resistant Staphylococcus aureus (MRSA).en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleCurrent Infectious Disease Reportsen_US
dc.identifier.affiliationInfectious Diseasesen_US
dc.identifier.doi10.1007/s11908-012-0254-8en_US
dc.description.pages330-8en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/22430229en
dc.type.contentTexten_US
dc.type.austinJournal Articleen
local.name.researcherCharles, Patrick G P
item.languageiso639-1en-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptMicrobiology-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptGeneral Medicine-
crisitem.author.deptInfectious Diseases-
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