Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11444
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dc.contributor.authorTsang, Benjamin K-T-
dc.contributor.authorCrump, Nicholas H-
dc.contributor.authorMacdonell, Richard A L-
dc.date.accessioned2015-05-16T01:03:18Z
dc.date.available2015-05-16T01:03:18Z
dc.date.issued2012-02-18-
dc.identifier.citationJournal of Clinical Neuroscience 2012; 19(6): 908-10en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11444en
dc.description.abstractWe describe a 35 year-old man presenting with a four-week history of non-painful limb paraesthesias and unsteady gait causing falls. On examination he had an ataxic gait associated with dorsal column sensory loss. He had a medical history of a partial gastrectomy six years prior and anaemia. He had received monthly intramuscular hydroxycobalamin injections since the gastrectomy. Laboratory tests revealed normal vitamin B12 and holotranscobalamin levels, a reduced serum caeruloplasmin of 0.05 g/L (normal: 0.22-0.58 g/L), a copper-to-caeruloplasmin ratio of 1.9 μmol/L (11.0-22.0 μmol/L) and a reduced 24-hour urinary copper concentration of <0.30 μmol/L (0-0.3 μmol/L). Cerebrospinal fluid analysis, nerve conduction studies, electromyography and visual-evoked responses were unremarkable. MRI revealed abnormal hyperintense signal in the cervical dorsal columns. Hypocupric myelopathy was diagnosed and he was treated with daily oral elemental copper. Three months later, his walking and balance had improved although there was no change noted on MRI.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherGait Ataxia.complications.diet therapyen
dc.subject.otherHumansen
dc.subject.otherLongitudinal Studiesen
dc.subject.otherMagnetic Resonance Imagingen
dc.subject.otherMaleen
dc.subject.otherSensation Disorders.complications.diet therapyen
dc.subject.otherSpinal Cord.pathologyen
dc.subject.otherSpinal Cord Diseases.complications.etiology.prevention & controlen
dc.subject.otherSubacute Combined Degeneration.complications.etiology.prevention & controlen
dc.subject.otherVitamin B 12.administration & dosageen
dc.titleSubacute combined degeneration of the spinal cord despite prophylactic vitamin B12 treatment.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Clinical Neuroscienceen
dc.identifier.affiliationDepartment of Neurology, The Austin Hospital, Austin Health, Studley Road, Heidelberg, Victoria 3084, Australiaen
dc.identifier.doi10.1016/j.jocn.2011.08.028en
dc.description.pages908-10en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/22342235en
dc.type.contentTexten
dc.type.austinJournal Articleen
local.name.researcherCrump, Nicholas H
item.grantfulltextnone-
item.openairetypeJournal Article-
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.deptNeurology-
crisitem.author.deptMedicine (University of Melbourne)-
crisitem.author.deptNeurology-
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