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Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual.

Author(s)
Davey, Rachel A
Clarke, Michele V
Sastra, Stephen
Skinner, Jarrod P
Chiang, Cherie Ying
Anderson, Paul H
Zajac, Jeffrey D
Publication Date
2011-12-13
Abstract
Conditional gene inactivation using the Cre/loxP system has lead to significant advances in our understanding of the function of genes in a wide range of disciplines. It is becoming increasingly apparent in the literature, that Cre transgenic mice may themselves have a phenotype. In the following study we describe the bone phenotype of a commonly used Cre transgenic mouse line to study osteoblasts, the Osx-GFP
Citation
Transgenic Research 2011; 21(4): 885-93
Jornal Title
Transgenic research
Link
Title
Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual.
Type of document
Journal Article

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