Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11317
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dc.contributor.authorTaylor, David McDen
dc.contributor.authorBell, Anthonyen
dc.contributor.authorHoldgate, Annaen
dc.contributor.authorMacBean, Catherine Een
dc.contributor.authorHuynh, Trucen
dc.contributor.authorThom, Ogilvieen
dc.contributor.authorAugello, Michaelen
dc.contributor.authorMillar, Roberten
dc.contributor.authorDay, Roberten
dc.contributor.authorWilliams, Aleden
dc.contributor.authorRitchie, Peteren
dc.contributor.authorPasco, Johnen
dc.date.accessioned2015-05-16T00:54:23Z
dc.date.available2015-05-16T00:54:23Z
dc.date.issued2011-05-17en
dc.identifier.citationEmergency Medicine Australasia : EMA 2011; 23(4): 466-73en
dc.identifier.govdoc21824314en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11317en
dc.description.abstractTo determine the nature, incidence and risk factors for sedation-related events during ED procedural sedation, with particular focus on the drugs administered.Eleven Australian EDs enrolled consecutive adult and paediatric patients between January 2006 and December 2008. Patients were included if a sedative drug was administered for an ED procedure. Data collection was prospective and employed a specifically designed form. Multivariate logistic regression was employed to determine risk factors for sedation-related events.Two thousand, six hundred and twenty-three patients were enrolled (60.3% male, mean age 39.2 years). Reductions of fracture/dislocations of shoulders, wrists and ankles were most common. Four hundred and sixty-one (17.6%) cases experienced at least one airway event that required intervention. Airway obstruction, hypoventilation and desaturation occurred in 12.7%, 6.4% and 3.7% of all patients, respectively. Two thousand, one hundred and forty-six cases had complete datasets for further analyses. Increasing age and level of sedation, pre-medication with fentanyl, and sedation with propofol, midazolam or fentanyl were risk factors for an airway event (P < 0.05). Ketamine was a protective factor. Hypotension (systolic pressure <80 mmHg) occurred in 34 (1.6%) cases with midazolam being a significant risk factor (P < 0.001). Vomiting also occurred in 34 (1.6%) cases, 12 of whom required an intervention. One patient aspirated. Vomiting occurred after administration of all drugs but was not associated with fasting status. Other events were rare.Sedation-related events, especially airway events, are common but very rarely have an adverse outcome. Elderly patients, deeply sedated with short-acting agents, are at particular risk. The results will help tailor sedation to individual patients.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherAge Factorsen
dc.subject.otherAustralia.epidemiologyen
dc.subject.otherConscious Sedation.adverse effectsen
dc.subject.otherEmergency Service, Hospitalen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherHypnotics and Sedatives.adverse effectsen
dc.subject.otherHypotension.chemically induced.epidemiologyen
dc.subject.otherIncidenceen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherMultivariate Analysisen
dc.subject.otherRespiration Disorders.chemically induced.epidemiologyen
dc.subject.otherRisk Factorsen
dc.subject.otherVomiting.chemically induced.epidemiologyen
dc.subject.otherYoung Adulten
dc.titleRisk factors for sedation-related events during procedural sedation in the emergency department.en
dc.typeJournal Articleen
dc.identifier.journaltitleEmergency Medicine Australasia : EMAen
dc.identifier.affiliationAustin Hospital, Melbourne, Victoria, Australiaen
dc.identifier.doi10.1111/j.1742-6723.2011.01419.xen
dc.description.pages466-73en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/21824314en
dc.type.austinJournal Articleen
local.name.researcherMillar, Robert
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptEmergency-
crisitem.author.deptEmergency-
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