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dc.contributor.authorJerums, Georgeen
dc.contributor.authorMacIsaac, Richard Jen
dc.date.accessioned2015-05-16T00:53:07Z-
dc.date.available2015-05-16T00:53:07Z-
dc.date.issued2011-06-28en
dc.identifier.citationDiabetologia 2011; 54(9): 2223-5en
dc.identifier.govdoc21710288en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11296en
dc.description.abstractIn this issue of Diabetologia, two new approaches are described for the assessment of intra-renal blood flow in people with diabetes. The first approach used the technique of dynamic assessment of the resistance index (RI) in the renal interlobar arteries before and after administration of sublingual glyceryl trinitrate, and the second used MRI to assess total renal blood flow in relation to mean arterial pressure, thereby enabling direct measurement of overall renal RI. The results of the first study raise the possibility that dynamic evaluation of the intra-renal RI could be used as an early detector of vascular alterations in type 2 diabetes, before the onset of microalbuminuria. The results of the second study suggest that decreases in renal blood flow in people with longstanding type 1 diabetes reflect intra-renal vascular stiffening and raise the possibility that in microalbuminuric patients it may also reflect increased intraglomerular pressure.en
dc.language.isoenen
dc.subject.otherAlbuminuria.physiopathologyen
dc.subject.otherDiabetes Mellitus, Type 1.complications.pathologyen
dc.subject.otherDiabetes Mellitus, Type 2.physiopathologyen
dc.subject.otherDiabetic Nephropathies.etiology.pathologyen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherHypertension.physiopathologyen
dc.subject.otherKidney.blood supplyen
dc.subject.otherMagnetic Resonance Imaging.methodsen
dc.subject.otherMaleen
dc.subject.otherRegional Blood Flow.physiologyen
dc.titleNew approaches for the evaluation of renal vascular function in diabetes.en
dc.typeJournal Articleen
dc.identifier.journaltitleDiabetologiaen
dc.identifier.affiliationEndocrine Centre, Austin Health & University of Melbourne, Heidelberg Repatriation Hospital, Heidelberg West, PO Box 5444, VIC 3081, Australiaen
dc.identifier.doi10.1007/s00125-011-2225-2en
dc.description.pages2223-5en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/21710288en
dc.type.austinJournal Articleen
local.name.researcherJerums, George
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
crisitem.author.deptEndocrinology-
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