Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/11232| Title: | High-affinity platelet [3H]LSD binding is decreased in panic disorder. | Austin Authors: | Norman, Trevor R ;Judd, F K;Staikos, V;Burrows, Graham D;McIntyre, I M | Affiliation: | Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia | Issue Date: | 1-Jun-1990 | Publication information: | Journal of Affective Disorders; 19(2): 119-23 | Abstract: | Platelet [3H]LSD binding was measured in 15 patients with panic attacks and 15 controls. The mean (+/- SD) Bmax values of the patients (14.1 +/- 6.3 fmol/mg protein) and of the controls (18.5 +/- 4.7 fmol/mg protein) were significantly different (P less than 0.05, Mann-Whitney U-test). Mean (+/- SD) values of Kd for the patients (0.55 +/- 0.34 nM) and for the controls (0.51 +/- 0.12 nM) were not significantly different (P greater than 0.1, Mann-Whitney U-test). The results are discussed in terms of a serotonergic hypothesis of the aetiology of panic disorders. | Gov't Doc #: | 2142698 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/11232 | Journal: | Journal of affective disorders | URL: | https://pubmed.ncbi.nlm.nih.gov/2142698 | Type: | Journal Article | Subjects: | Adult Agoraphobia.blood.psychology Blood Platelets.metabolism Fear.physiology Female Humans Lysergic Acid Diethylamide.pharmacokinetics Male Middle Aged Panic.physiology Personality Tests Receptors, Serotonin.metabolism Sex Factors |
| Appears in Collections: | Journal articles |
Show full item record
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.