Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11055
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dc.contributor.authorProwle, John Ren
dc.contributor.authorBellomo, Rinaldoen
dc.date.accessioned2015-05-16T00:38:02Z
dc.date.available2015-05-16T00:38:02Z
dc.date.issued2010-08-01en
dc.identifier.citationCurrent Opinion in Critical Care; 16(4): 332-6en
dc.identifier.govdoc20543683en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/11055en
dc.description.abstractIntravenous fluids are widely administered in the ICU with the intention of preventing or ameliorating acute kidney injury (AKI). This review focuses on recent studies examining fluid administration and renal function in critical illness to critically examine conventional justifications for fluid administration.Early, targeted, resuscitation of inadequate cardiac output in shock may have a beneficial effect on organ function and patient outcome. However, experimental evidence suggests the relationship between fluid administration and an increase in renal oxygen delivery is weak, whereas any beneficial effects from fluid administration can be short lived. Conversely, evidence associating fluid overload and adverse outcomes is strengthening, whereas more restrictive fluid administration does not seem to predispose to clinically significant AKI in many situations. Furthermore, concerns persist that some colloid or high chloride concentration solutions may directly impair renal function independent of volume overload.Adequate volume resuscitation remains a cornerstone to the emergent treatment of critical illness. However, continued fluid administration and positive fluid balances have not been shown to improve renal outcomes and may worsen overall prognosis in AKI. Concerns about renal dysfunction should not deter clinicians from adopting more restrictive approaches to fluid administration.en
dc.language.isoenen
dc.subject.otherCardiac Outputen
dc.subject.otherCritical Care.methodsen
dc.subject.otherCritical Illnessen
dc.subject.otherFluid Therapy.methodsen
dc.subject.otherGlomerular Filtration Rateen
dc.subject.otherHemodynamicsen
dc.subject.otherHumansen
dc.subject.otherInfusions, Intravenous.methodsen
dc.subject.otherIntensive Care Unitsen
dc.subject.otherIsotonic Solutions.administration & dosageen
dc.subject.otherKidney.physiologyen
dc.subject.otherPrognosisen
dc.subject.otherShock, Cardiogenic.prevention & controlen
dc.titleFluid administration and the kidney.en
dc.typeJournal Articleen
dc.identifier.journaltitleCurrent opinion in critical careen
dc.identifier.affiliationDepartment of Intensive Care, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1097/MCC.0b013e32833be90ben
dc.description.pages332-6en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/20543683en
dc.type.austinJournal Articleen
item.grantfulltextnone-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
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