Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11023
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dc.contributor.authorBellomo, Rinaldoen
dc.contributor.authorProwle, John Ren
dc.contributor.authorEcheverri, Jorge Een
dc.contributor.authorLigabo, Valentinaen
dc.contributor.authorRonco, Claudioen
dc.date.accessioned2015-05-16T00:36:07Z-
dc.date.available2015-05-16T00:36:07Z-
dc.date.issued2010-04-20en
dc.identifier.citationContributions To Nephrology 2010; 165(): 206-18en
dc.identifier.govdoc20427971en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11023en
dc.description.abstractIntravenous fluids are commonly administered to patients with developing septic acute kidney injury (AKI). Conversely, fluids are just as commonly removed with diuretics or renal replacement therapy (RRT) techniques or ultrafiltration in patients with cardiorenal syndromes (CRS). In both groups, there is controversy regarding fluid management. However, in patients with septic AKI, the deleterious consequences of overzealous fluid therapy are increasingly being recognized, while concerns exist both about the possible adverse effects of excessive and/or insufficient fluid removal with diuretics or ultrafiltration in CRS. In this article, we discuss how interstitial edema can further delay renal recovery and why conservative fluid strategies are now being advocated in septic AKI. In patients with septic AKI, this strategy might require RRT to be given earlier to assist with fluid removal. However, in patients with either septic AKI or CRS, hypovolemia and renal hypoperfusion can occur if excessive fluid removal is pursued with diuretics or extracorporeal therapy. Thus, accurate assessment of fluid status and careful definition of targets are needed to improve clinical outcomes. Controlled studies of conservative versus liberal fluid management in patients with AKI or CRS seem justified.en
dc.language.isoenen
dc.subject.otherAcute Kidney Injury.complications.etiology.physiopathology.therapyen
dc.subject.otherBlood Pressureen
dc.subject.otherCardiac Output, Low.complications.physiopathologyen
dc.subject.otherCentral Venous Pressure.physiologyen
dc.subject.otherCritical Illnessen
dc.subject.otherDiuretics.adverse effects.therapeutic useen
dc.subject.otherEdema.etiology.physiopathologyen
dc.subject.otherExtracellular Fluid.physiologyen
dc.subject.otherFluid Therapy.adverse effectsen
dc.subject.otherGlomerular Filtration Rateen
dc.subject.otherHeart Diseases.complications.physiopathology.therapyen
dc.subject.otherHumansen
dc.subject.otherKidney Glomerulus.physiopathologyen
dc.subject.otherKidney Tubules.physiopathologyen
dc.subject.otherRenal Replacement Therapy.methodsen
dc.subject.otherShock, Septic.complications.therapyen
dc.subject.otherSyndromeen
dc.titleFluid management in septic acute kidney injury and cardiorenal syndromes.en
dc.typeJournal Articleen
dc.identifier.journaltitleContributions to nephrologyen
dc.identifier.affiliationDepartment of Intensive Care, Austin Health, Heidelberg, Melbourne, Victoria, Australiaen
dc.identifier.doi10.1159/000313760en
dc.description.pages206-18en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/20427971en
dc.type.austinJournal Articleen
local.name.researcherBellomo, Rinaldo
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
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