Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10931
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dc.contributor.authorDonnan, Geoffrey Aen
dc.contributor.authorBladin, Peter Fen
dc.contributor.authorBerkovic, Samuel Fen
dc.contributor.authorLongley, W Aen
dc.contributor.authorSaling, Michael Men
dc.date.accessioned2015-05-16T00:30:32Z
dc.date.available2015-05-16T00:30:32Z
dc.date.issued1991-02-01en
dc.identifier.citationBrain : A Journal of Neurology; 114 ( Pt 1A)(): 51-70en
dc.identifier.govdoc1998890en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/10931en
dc.description.abstractStriatocapsular infarction has recently been described as a distinct stroke entity and forms an important subgroup of subcortical infarctions. In a prospective study of 50 consecutive patients over a 10 yr period with this syndrome, clinical and neuropsychological features, pathogenesis and outcome were studied to provide information concerning management and prognosis. The most common clinical presentation was that of a stroke affecting mainly the upper limb with cortical signs such as dysphasia, neglect or dyspraxia. Evidence from EEG, angiographic and neuropsychological data supported a vascular/haemodynamic basis for the presence of the acute neuropsychological changes, while the chronic changes were more likely to be due to diaschisis. A study of risk factors and cerebral angiography enabled 4 pathophysiological subgroups to be identified: (1) cardiac emboli to the origin of the middle cerebral artery; (2) severe extra-cranial cranial carotid artery occlusive disease with presumed embolism to the same site and/or involvement of haemodynamic factors; (3) proximal middle cerebral artery abnormalities causing occlusion of multiple lateral striate arteries at their origins; (4) normal angiography where pathogenesis was uncertain. The risk factors of cardiac disease and smoking were significantly increased as compared with age and sex-matched controls with other forms of ischaemic stroke. Stroke or vascular death rate was 2.7% per yr during a mean follow-up period of 2.25 yrs. Predictors of an excellent recovery with return to normal lifestyle were younger age, only brachial or brachiofacial weakness with absence of cortical signs at presentation and minimal change on angiography. This stroke entity deserves particular recognition in the spectrum of subcortical infarctions because of its specific pathogenesis, distinct neuropsychological features and reasonable prognosis.en
dc.language.isoenen
dc.subject.otherCerebral Angiographyen
dc.subject.otherCerebral Infarction.physiopathology.radiographyen
dc.subject.otherCerebrovascular Disorders.physiopathology.radiographyen
dc.subject.otherCorpus Striatum.physiopathology.radiographyen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherNeuropsychological Testsen
dc.subject.otherPrognosisen
dc.subject.otherProspective Studiesen
dc.subject.otherRisk Factorsen
dc.subject.otherSyndromeen
dc.subject.otherTomography, X-Ray Computeden
dc.titleThe stroke syndrome of striatocapsular infarction.en
dc.typeJournal Articleen
dc.identifier.journaltitleBrainen
dc.identifier.affiliationDepartment of Neurology, Austin Hospital, Melbourne, Australiaen
dc.description.pages51-70en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/1998890en
dc.type.austinJournal Articleen
local.name.researcherBerkovic, Samuel F
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptThe Florey Institute of Neuroscience and Mental Health-
crisitem.author.deptNeurology-
crisitem.author.deptEpilepsy Research Centre-
crisitem.author.deptNeurology-
crisitem.author.deptClinical Neuropsychology-
crisitem.author.deptThe Florey Institute of Neuroscience and Mental Health-
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