Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10928
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dc.contributor.authorBarnes, Mareeen
dc.contributor.authorGoldsworthy, Unna Raquelen
dc.contributor.authorCary, Belinda Annen
dc.contributor.authorHill, Catherine Janeen
dc.date.accessioned2015-05-16T00:30:20Z
dc.date.available2015-05-16T00:30:20Z
dc.date.issued2009-10-15en
dc.identifier.citationJournal of Clinical Sleep Medicine : Jcsm : Official Publication of the American Academy of Sleep Medicine; 5(5): 409-15en
dc.identifier.govdoc19961023en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/10928en
dc.description.abstractTo assess the feasibility and efficacy of a novel 16-week exercise and diet program for important clinical outcomes in obstructive sleep apnea (OSA).Cohort study assessing sleep disordered breathing, cardiovascular risk factors, and neurobehavioral function prior to and following completion of the 16-week program. The program used a proprietary very low energy diet (Optifast, Novartis), and subjects participated in a supervised exercise schedule, which included both aerobic and resistance training. Follow-up contact was made at 12 months after program exit. Consecutive patients with newly diagnosed sleep apnea were approached who had an apnea-hypopnea index (AHI) of 10 to 50, a body mass index (BMI) of greater than 30 kg/m2, no significant comorbidities, and able to exercise.All data are presented as mean [SD]. Of 21 patients with OSA who were approached, 12 middle-aged (42.3 [10.4] years old), obese (BMI 36.1 [4.3] kg/m2), and predominantly female (75%) subjects with mild to moderate OSA were enrolled (AHI 24.6 [12.0]). Weight loss was significant (12.3 [9.6] kg, p <0.001), and 5 of the 10 who completed the program were able to independently maintain good weight loss at 12 months. At the 16-week assessment, there was a small nonsignificant fall in the AHI. Six of the 10 subjects had a reduction in sleep disordered breathing, and the AHI was less than 10 in 3 patients. There were significant improvements in neurobehavioral and cardiometabolic outcomes. Snoring improved in most subjects, but the improvement was clinically important (a score of < 2) in only 7.A supportive diet and exercise program may be of benefit to obese patients with mild to moderate sleep apnea. The results of this feasibility study showed significant weight loss and improvement in clinically important neurobehavioral and cardiometabolic outcomes but no significant change in sleep disordered breathing. These promising preliminary results need confirmation with a larger randomized trial.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherAffecten
dc.subject.otherBlood Glucose.analysisen
dc.subject.otherBlood Pressureen
dc.subject.otherBody Mass Indexen
dc.subject.otherCohort Studiesen
dc.subject.otherDiet, Reducing.methodsen
dc.subject.otherExercise Therapy.methodsen
dc.subject.otherFeasibility Studiesen
dc.subject.otherFemaleen
dc.subject.otherFollow-Up Studiesen
dc.subject.otherHumansen
dc.subject.otherInsulin.blooden
dc.subject.otherLipids.blooden
dc.subject.otherMaleen
dc.subject.otherPolysomnographyen
dc.subject.otherQuality of Lifeen
dc.subject.otherSleep Apnea, Obstructive.therapyen
dc.subject.otherTreatment Outcomeen
dc.subject.otherWeight Lossen
dc.titleA diet and exercise program to improve clinical outcomes in patients with obstructive sleep apnea--a feasibility study.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicineen
dc.identifier.affiliationInstitute for Breathing and Sleep, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages409-15en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/19961023en
dc.type.austinJournal Articleen
local.name.researcherBarnes, Maree
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
crisitem.author.deptInstitute for Breathing and Sleep-
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