Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10920
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dc.contributor.authorAzad, Arun Aen
dc.contributor.authorChionh, Fionaen
dc.contributor.authorScott, Andrew Men
dc.contributor.authorLee, Szeting Ten
dc.contributor.authorBerlangieri, Salvatore Uen
dc.contributor.authorWhite, Shane Cen
dc.contributor.authorMitchell, Paul L Ren
dc.date.accessioned2015-05-16T00:29:51Z
dc.date.available2015-05-16T00:29:51Z
dc.date.issued2009-11-17en
dc.identifier.citationMolecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging 2009; 12(4): 443-51en
dc.identifier.govdoc19921339en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/10920en
dc.description.abstractWe evaluated whether 18F-FDG-PET altered stage classification, management, and prognostic stratification of newly diagnosed small cell lung cancer (SCLC).We identified 46 consecutive patients undergoing staging positron emission tomography for SCLC from 1993-2008 inclusive. Updated survival data from the state Cancer Registry was available on 42 of 46 patients.PET altered stage classification in 12 of 46 (26%) patients. PET altered treatment modality in nine patients, and the target mediastinal radiation field in another three patients. Therefore, PET altered management in 12 of 46 (26%) patients. Patients with limited disease (LD) on pre-PET staging had significantly longer overall survival (OS) than those upstaged to extensive disease (ED; median 18.6 months versus 5.7 months; log-rank p < 0.0001). In patients with ED on pre-PET staging, those downstaged to LD by PET had significantly longer OS than those with ED on PET (median 10.9 months versus 5.9 months; log-rank p = 0.037).PET had a major impact on stage classification, management, and prognostic stratification of newly diagnosed SCLC.en
dc.language.isoenen
dc.subject.otherAgeden
dc.subject.otherFemaleen
dc.subject.otherFluorodeoxyglucose F18.diagnostic useen
dc.subject.otherHumansen
dc.subject.otherKaplan-Meier Estimateen
dc.subject.otherLung Neoplasms.pathology.radiography.radionuclide imaging.therapyen
dc.subject.otherMaleen
dc.subject.otherNeoplasm Stagingen
dc.subject.otherPositron-Emission Tomographyen
dc.subject.otherPrognosisen
dc.subject.otherProportional Hazards Modelsen
dc.subject.otherSmall Cell Lung Carcinoma.pathology.radiography.radionuclide imaging.therapyen
dc.subject.otherTomography, X-Ray Computeden
dc.titleHigh impact of 18F-FDG-PET on management and prognostic stratification of newly diagnosed small cell lung cancer.en
dc.typeJournal Articleen
dc.identifier.journaltitleMolecular imaging and biology : MIB : the official publication of the Academy of Molecular Imagingen
dc.identifier.affiliationLudwig Institute Oncology Unit, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1007/s11307-009-0295-zen
dc.description.pages443-51en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/19921339en
dc.type.austinJournal Articleen
local.name.researcherBerlangieri, Salvatore U
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairetypeJournal Article-
crisitem.author.deptMolecular Imaging and Therapy-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
crisitem.author.deptClinical Haematology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptMedical Oncology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
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