Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/10878
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Darren | - |
dc.contributor.author | Haase, Michael | - |
dc.contributor.author | Haase-Fielitz, Anja | - |
dc.contributor.author | Paizis, Kathy | - |
dc.contributor.author | Goehl, Hermann | - |
dc.contributor.author | Bellomo, Rinaldo | - |
dc.date.accessioned | 2015-05-16T00:27:21Z | |
dc.date.available | 2015-05-16T00:27:21Z | |
dc.date.issued | 2009-09-03 | - |
dc.identifier.citation | Blood Purification 2009; 28(4): 365-72 | en_US |
dc.identifier.other | PUBMED | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/10878 | en |
dc.description.abstract | High cut-off (HCO) membranes may increase beta(2)-microglobulin (beta2M) removal compared to standard high-flux membranes.Eight stable haemodialysis patients were enrolled in a prospective, randomized, double-blind, cross-over study and treated with HCO and high-flux membranes for 2 weeks each, between a 1-week washout period. Primary end point was serum beta2M removal. Secondary end points included serum albumin concentrations, albumin and small solute clearances.HCO membranes achieved significantly lower median post-dialysis beta2M concentration (10.8 vs. 14.2 mg/l; p = 0.003) and greater beta2M reduction ratio (62.3 vs. 51.0%; p < 0.002). Serum albumin decreased with HCO membranes (from 36 to 29.5 g/l; p = 0.018) but increased to 33.5 g/l after the washout period. Albumin clearance was significantly greater with HCO membranes (2.2 vs. 0.06 ml/min; p = 0.004). Urea reduction ratio was significantly lower with HCO membranes (64.8 vs. 71.5%; p < 0.001).beta2M removal was superior with HCO membranes. Reduction in serum albumin and lower small solute clearance require further investigations. | en_US |
dc.language.iso | en | en |
dc.subject.other | Aged | en |
dc.subject.other | Cross-Over Studies | en |
dc.subject.other | Double-Blind Method | en |
dc.subject.other | Female | en |
dc.subject.other | Humans | en |
dc.subject.other | Male | en |
dc.subject.other | Materials Testing | en |
dc.subject.other | Membranes, Artificial | en |
dc.subject.other | Middle Aged | en |
dc.subject.other | Renal Dialysis.instrumentation | en |
dc.subject.other | Serum Albumin.analysis | en |
dc.subject.other | Treatment Outcome | en |
dc.subject.other | beta 2-Microglobulin.blood | en |
dc.title | A pilot, randomized, double-blind, cross-over study of high cut-off versus high-flux dialysis membranes. | en_US |
dc.type | Journal Article | en_US |
dc.identifier.journaltitle | Blood Purification | en_US |
dc.identifier.affiliation | Nephrology | en_US |
dc.identifier.doi | 10.1159/000235961 | en_US |
dc.description.pages | 365-72 | en |
dc.relation.url | https://pubmed.ncbi.nlm.nih.gov/19729908 | en |
dc.type.content | Text | en_US |
dc.type.austin | Journal Article | en |
local.name.researcher | Bellomo, Rinaldo | |
item.languageiso639-1 | en | - |
item.openairetype | Journal Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Nephrology | - |
crisitem.author.dept | Intensive Care | - |
crisitem.author.dept | Data Analytics Research and Evaluation (DARE) Centre | - |
Appears in Collections: | Journal articles |
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