Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/10701
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chan, Lie S | en |
dc.contributor.author | Daruwalla, Jurstine | en |
dc.contributor.author | Christophi, Christopher | en |
dc.date.accessioned | 2015-05-16T00:14:14Z | |
dc.date.available | 2015-05-16T00:14:14Z | |
dc.date.issued | 2008-11-01 | en |
dc.identifier.citation | ANZ Journal of Surgery; 78(11): 955-67 | en |
dc.identifier.govdoc | 18959693 | en |
dc.identifier.other | PUBMED | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/10701 | en |
dc.description.abstract | Selective targeting of the tumour vasculature in the treatment of solid organ malignancies is an alternative to conventional chemotherapy treatment. As the tumour progressively increases in size, angiogenesis or the formation of new vasculature is essential to maintain the tumour's continual growth and survival. Therefore disrupting this angiogenic process or targeting the neovasculature can potentially hinder or prevent further tumour expansion. Many anti angiogenic agents have been investigated with many currently in clinical trials and exhibiting varied results. Vascular disrupting agents such as the Combretastatins and OXi 4503 have shown promising preclinical results and are currently being examined in clinical trials. | en |
dc.language.iso | en | en |
dc.subject.other | Angiogenesis Inhibitors.therapeutic use | en |
dc.subject.other | Humans | en |
dc.subject.other | Neoplasms.blood supply.drug therapy | en |
dc.subject.other | Neovascularization, Pathologic.prevention & control | en |
dc.title | Selective targeting of the tumour vasculature. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | ANZ Journal of Surgery | en |
dc.identifier.affiliation | Department of Surgery, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia | en |
dc.identifier.doi | 10.1111/j.1445-2197.2008.04712.x | en |
dc.description.pages | 955-67 | en |
dc.relation.url | https://pubmed.ncbi.nlm.nih.gov/18959693 | en |
dc.type.austin | Journal Article | en |
local.name.researcher | Christophi, Christopher | |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Hepatopancreatobiliary Surgery | - |
Appears in Collections: | Journal articles |
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