Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10594
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dc.contributor.authorBellomo, Rinaldoen
dc.contributor.authorReade, Michael Cen
dc.contributor.authorWarrillow, Stephen Jen
dc.date.accessioned2015-05-16T00:06:10Z-
dc.date.available2015-05-16T00:06:10Z-
dc.date.issued2008-04-07en
dc.identifier.citationCritical Care 2008; 12(2): 130en
dc.identifier.govdoc18423058en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/10594en
dc.description.abstractIn this issue of Critical Care, Dutch investigators report that, in a cohort of patients with sepsis/septic shock admitted to three different intensive care units (ICUs), low central venous oxygen saturation (ScvO2) was uncommon at the time of ICU admission, and hospital mortality was <30%. Their findings, taken together with those of recent reports from Australia and New Zealand (ANZ), raise serious concerns about the utility of early goal directed therapy (EGDT) outside the context of the original trial. Despite inclusion of EGDT into the Surviving Sepsis Guidelines, in response to growing uncertainty, ANZ and US investigators will soon begin randomization of patients into two large multicentre trials comparing EGDT to standard therapy. Until such studies are completed, basing international treatment guidelines on a single centre study performed in what may turn out to be a highly atypical environment would seem premature.en
dc.language.isoenen
dc.subject.otherAPACHEen
dc.subject.otherAgeden
dc.subject.otherBlood Gas Analysis.methodsen
dc.subject.otherCritical Illnessen
dc.subject.otherFemaleen
dc.subject.otherHematocriten
dc.subject.otherHumansen
dc.subject.otherHydrogen-Ion Concentrationen
dc.subject.otherIncidenceen
dc.subject.otherIntensive Care Unitsen
dc.subject.otherLactates.blooden
dc.subject.otherMaleen
dc.subject.otherNetherlandsen
dc.subject.otherObservationen
dc.subject.otherOxygen.blooden
dc.subject.otherPrognosisen
dc.subject.otherShock, Septic.blooden
dc.titleThe pursuit of a high central venous oxygen saturation in sepsis: growing concerns.en
dc.typeJournal Articleen
dc.identifier.journaltitleCritical Careen
dc.identifier.affiliationDepartment of Intensive Care, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1186/cc6841en
dc.description.pages130en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/18423058en
dc.type.austinJournal Articleen
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.grantfulltextopen-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
crisitem.author.deptIntensive Care-
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