Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10298
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dc.contributor.authorEgi, Moritokien
dc.contributor.authorBellomo, Rinaldoen
dc.contributor.authorStachowski, Edwarden
dc.contributor.authorFrench, Craig Jen
dc.contributor.authorHart, Graeme Ken
dc.contributor.authorStow, Peteren
dc.date.accessioned2015-05-15T23:42:32Z
dc.date.available2015-05-15T23:42:32Z
dc.date.issued2007-02-01en
dc.identifier.citationCritical Care Medicine; 35(2): 416-21en
dc.identifier.govdoc17205020en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/10298en
dc.description.abstractTo test whether there is a circadian rhythm of blood glucose control in critically ill patients and whether morning blood glucose is an accurate surrogate of overall blood glucose control.Retrospective multiple-center observational study.Intensive care units of three tertiary hospitals and one affiliated private hospital.Cohort of 8,307 consecutive critically ill patients.Extraction of blood glucose values from electronically stored measurements. Extraction of demographic and outcome data from unit and hospital databases. Statistical assessment of variations in blood glucose control over each 24-hr cycle.We studied 208,362 blood glucose measurements in 8,307 patients (5.5 measurements/day/person). In each hospital, there was a circadian rhythm of blood glucose control (p<.0001). The differences between highest and lowest blood glucose concentration in different time periods in each hospital were 0.27, 0.28, 0.95, and 0.22 mmol/L. There was also significant variation in the incidence and notional duration of hyperglycemia. The differences between the lowest and highest incidence of hyperglycemia in different time periods were 3.3, 2.7, 9.9, and 2.6% in each hospital. In all four hospitals, the average blood glucose value from 5:30 am to 6:30 am was significantly lower than the 24-hr average.Blood glucose values and the incidence of hyperglycemia have a circadian rhythm in critically ill patients. Morning blood glucose may not be an accurate surrogate of blood glucose control over the daily cycle.en
dc.language.isoenen
dc.subject.otherAgeden
dc.subject.otherBlood Glucose.analysisen
dc.subject.otherCircadian Rhythmen
dc.subject.otherCritical Illnessen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherHyperglycemia.blood.epidemiologyen
dc.subject.otherHypoglycemia.blood.epidemiologyen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherRetrospective Studiesen
dc.titleCircadian rhythm of blood glucose values in critically ill patients.en
dc.typeJournal Articleen
dc.identifier.journaltitleCritical Care Medicineen
dc.identifier.affiliationDepartment of Intensive Care, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1097/01.CCM.0000253814.78836.43en
dc.description.pages416-21en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/17205020en
dc.type.austinJournal Articleen
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.languageiso639-1en-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
crisitem.author.deptIntensive Care-
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