Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9585
Full metadata record
DC FieldValueLanguage
dc.contributor.authorNayler, W Gen
dc.date.accessioned2015-05-15T22:44:17Z
dc.date.available2015-05-15T22:44:17Z
dc.date.issued1992-05-16en
dc.identifier.citationJournal of Cardiovascular Pharmacology; 19 Suppl 2(): S17-21en
dc.identifier.govdoc1377299en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/9585en
dc.description.abstractCalcium is a ubiquitous cation involved in a wide variety of physiological processes. Normally, cytosolic calcium is maintained within narrow limits but under certain conditions the levels rise--either because of excess calcium entry, internal release, or failure of the extrusion mechanisms. Such conditions include hypertension and myocardial ischemia. Calcium ions are also involved in the formation of atherosclerotic lesions. Hypertension, ischemic heart disease, and atherosclerosis are all amenable to calcium antagonist therapy. The efficacy of this class of drugs in the management of such a wide spectrum of disorders is in accord with the central role played by calcium in the etiology of these disorders. To some extent, however, the disorders are interrelated, with hypertension being a major risk factors for ischemic heart disease and atherosclerosis.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherArteriosclerosis.drug therapy.prevention & controlen
dc.subject.otherCalcium.metabolismen
dc.subject.otherCoronary Disease.drug therapy.metabolismen
dc.subject.otherCytosol.drug effects.metabolismen
dc.subject.otherHumansen
dc.subject.otherHypercholesterolemia.drug therapyen
dc.subject.otherHypertension.drug therapy.physiopathologyen
dc.subject.otherMaleen
dc.subject.otherNifedipine.therapeutic useen
dc.subject.otherNitrendipine.therapeutic useen
dc.subject.otherRabbitsen
dc.subject.otherRatsen
dc.subject.otherRats, Inbred SHRen
dc.subject.otherRats, Inbred WKYen
dc.titleCalcium, calcium antagonism, atherosclerosis, and ischemia.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Cardiovascular Pharmacologyen
dc.identifier.affiliationDepartment of Medicine, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pagesS17-21en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/1377299en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
Appears in Collections:Journal articles
Show simple item record

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.