Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9555
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dc.contributor.authorVajda, F Jen
dc.date.accessioned2015-05-15T22:41:55Z
dc.date.available2015-05-15T22:41:55Z
dc.date.issued1992-08-01en
dc.identifier.citationCurrent Opinion in Neurology and Neurosurgery; 5(4): 519-25en
dc.identifier.govdoc1325225en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/9555en
dc.description.abstractThe development of antiepileptic drugs has been rather slow, and this may be related partly to the regulatory requirement to show unequivocal benefit of a new agent over existing drugs. There is a need to reconsider trial protocols to achieve this objective. Five new drugs, vigabatrin (GVG), lamotrigine (LTG), gabapentin (GPT), felbamate and oxcarbazepine (OCBZ) appear to be the most widely tested and promising agents. Of the others, loreclezole and stiripentol (STP) are showing the highest potential for therapeutic application. Clobazam appears to be more effective than implied from earlier reports.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherAnticonvulsants.therapeutic useen
dc.subject.otherBrain.drug effects.physiopathologyen
dc.subject.otherEpilepsy.drug therapy.physiopathologyen
dc.subject.otherHumansen
dc.subject.otherReceptors, GABA-A.drug effects.physiologyen
dc.subject.otherSynaptic Transmission.drug effects.physiologyen
dc.subject.othergamma-Aminobutyric Acid.physiologyen
dc.titleNew anticonvulsants.en
dc.typeJournal Articleen
dc.identifier.journaltitleCurrent opinion in neurology and neurosurgeryen
dc.identifier.affiliationDepartment of Neurology, Austin Hospital, University of Melbourne, Heidelberg, Victoria, Australiaen
dc.description.pages519-25en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/1325225en
dc.type.austinJournal Articleen
item.languageiso639-1en-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
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