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Title: The self-reported Physical Activity Scale for the Elderly (PASE) is a valid and clinically applicable measure in lung cancer.
Austin Authors: Granger, Catherine L ;Parry, Selina M;Denehy, Linda
Affiliation: Institute for Breathing and Sleep
Department of Physiotherapy, The University of Melbourne, Level 7 Alan Gilbert Building, 161 Barry Street, Melbourne, Victoria, 3010, Australia
Department of Physiotherapy, Royal Melbourne Hospital, Grattan Street, Melbourne, Victoria, 3010, Australia
Issue Date: Nov-2015
Date: 2015-03-26
Publication information: Supportive care in cancer 2015; 23(11): 3211-3218
Abstract: Physical activity (PA) is an important outcome in lung cancer; however, there is lack of consensus as to the best method for assessment. The Physical Activity Scale for the Elderly (PASE) is a commonly used questionnaire. The aim of this study was to assess the clinimetric properties of the PASE in lung cancer, specifically validity, predictive utility and clinical applicability (floor/ceiling effects, responsiveness and minimal important difference [MID]). This is a prospective observational study. Sixty-nine participants (62 % male, median [IQR] age 68 years [61-74]) with lung cancer completed the PASE at diagnosis at 2, 4 and 6 months. Additional measures included movement sensors (steps/day), physical function, health-related quality of life, functional capacity (6-min walk distance [6MWD]), and muscle strength. Spearman's rank correlation coefficient was used to assess relationships. Linear regression analyses were conducted to determine predictive utility of the PASE for health status at 6 months. Responsiveness (effect size) and MID (distribution-based estimation) were calculated. The PASE was administered on 176 occasions. The PASE had moderate convergent validity with movement sensors (rho = 0.50 [95 %CI = 0.29-0.66], p < 0.005) and discriminated between participants classed as sedentary/insufficient/sufficient according to PA guidelines (p < 0.005). The PASE had fair-moderate construct validity with measures of physical function (rho = 0.57 [95 %CI = 0.46-0.66], p < 0.005), 6MWD (rho = 0.40 [95 %CI = 0.23-0.55], p < 0.005), and strength (rho = 0.37 [95 %CI = 0.18-0.54], p < 0.005). The PASE (at diagnosis) exhibited predictive utility for physical function (Bcoef = 0.35, p = 0.008) and quality of life (Bcoef = 0.35, p = 0.023) at 6 months. A small floor effect was observed (3 %); however, there was no ceiling effect. There was a small responsiveness to change (effect size = 0.23) and MID between 17 and 25 points. The PASE is a valid measure of self-reported PA in lung cancer.
DOI: 10.1007/s00520-015-2707-8
ORCID: 0000-0001-6169-370X
Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PubMed URL: 25808104
PubMed URL:
Type: Journal Article
Subjects: Clinimetric properties
Lung cancer
Physical activity
Appears in Collections:Journal articles

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