Austin Health

Title
Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
Publication Date
2021-07-29
Author(s)
Drewett, George P
Copaescu, Ana
DeLuca, Joseph
Holmes, Natasha E
Trubiano, Jason
Subject
Ambisome
CARPA
Intradermal testing
LAmB
Skin prick testing
Type of document
Journal Article
OrcId
0000-0002-9439-0251
DOI
10.1186/s13223-021-00582-x
Abstract
Allergic reaction to liposomal amphotericin B is rare. We report a case of cardiac arrest in a 64-year-old woman following liposomal amphotericin B infusion, requiring resuscitation. We also present the results of subsequent skin prick and intradermal testing to liposomal amphotericin on the patient and three healthy controls, highlighting the need for further research into the immunopathogenesis of this reaction.
Link
Citation
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology 2021; 17(1): 80
Jornal Title
Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
ISSN
1710-1484

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