Austin Health

Title
Castleman's disease masquerading as pancreatic neuroendocrine tumour.
Publication Date
2021-06-24
Author(s)
Gunda, Deepika
Naughton, Jack
Stevens, Sean
Perini, Marcos V
Subject
gastrointestinal surgery
general surgery
pancreas and biliary tract
Type of document
Journal Article
OrcId
0000-0002-5336-5295
DOI
10.1136/bcr-2021-242597
Abstract
Castleman's disease (CD) is a rare lymphoproliferative disorder. This case report, to the best of our knowledge, is the first report of CD simulating a pancreatic neuroendocrine tumour . The patient was a 58-year-old woman who initially presented with bilateral iritis and underwent investigation for possible systemic rheumatological disease. CT of the chest demonstrated an incidental finding of a well-demarcated retropancreatic mass. As the mass was found to enhance on DOTATATE (tetraazacyclododecanetetraacetic acid-DPhe1-Tyr3-octreotate) positron emission tomography, a diagnosis of pancreatic neuroendocrine tumour was made. The patient underwent an open distal pancreatectomy and splenectomy. Histopathological examination revealed the unexpected diagnosis of hyaline vascular CD of a lymph node posterior to the pancreas. After 2 years of follow-up, there is no evidence of disease recurrence.
Link
Citation
BMJ Case Reports 2021; 14(6): e242597
Jornal Title
BMJ Case Reports

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