Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/23331
Title: Extracorporeal Blood Purification and Organ Support in the Critically Ill Patient during COVID-19 Pandemic: Expert Review and Recommendation.
Authors: Ronco, Claudio;Bagshaw, Sean M;Bellomo, Rinaldo;Clark, William R;Husain-Syed, Faeq;Kellum, John A;Ricci, Zaccaria;Rimmelé, Thomas;Reis, Thiago;Ostermann, Marlies
Affiliation: Department of Intensive Care, Austin Health, Heidelberg, Victoria, Australia
Department of Critical Care Medicine, Center for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
International Renal Research Institute (IRRIV), San Bortolo Hospital, Vicenza, Italy
Department of Nephrology, University of Padova, Padova, Italy
EA 7426 "Pathophysiology of Injury-induced Immunosuppression", Pi3, Hospices Civils de Lyon - BioMérieux - Claude Bernard University Lyon, Lyon, France..
Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France
Centre for Integrated Critical Care, The University of Melbourne, Melbourne, Victoria, Australia
Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
Department of Critical Care, King's College London, Guy's & St Thomas' Hospital, London, United Kingdom
Department of Nephrology, Clinica de Doenças Renais de Brasilia, Brasilia, Brazil
Center for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Davidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana, USA
Department of Internal Medicine II, Division of Nephrology, Pulmonology and Critical Care Medicine, University Hospital Giessen and Marburg, Giessen, Germany
Department of Cardiology and Cardiac Surgery, Pediatric Cardiac Intensive Care Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy
Department of Critical Care, King's College London, Guy's & St Thomas' Hospital, London, United Kingdom
Issue Date: 26-May-2020
EDate: 2020-05-26
Citation: Blood purification 2020: 1-11
Abstract: Critically ill COVID-19 patients are generally admitted to the ICU for respiratory insufficiency which can evolve into a multiple-organ dysfunction syndrome requiring extracorporeal organ support. Ongoing advances in technology and science and progress in information technology support the development of integrated multi-organ support platforms for personalized treatment according to the changing needs of the patient. Based on pathophysiological derangements observed in COVID-19 patients, a rationale emerges for sequential extracorporeal therapies designed to remove inflammatory mediators and support different organ systems. In the absence of vaccines or direct therapy for COVID-19, extracorporeal therapies could represent an option to prevent organ failure and improve survival. The enormous demand in care for COVID-19 patients requires an immediate response from the scientific community. Thus, a detailed review of the available technology is provided by experts followed by a series of recommendation based on current experience and opinions, while waiting for generation of robust evidence from trials.
URI: http://ahro.austin.org.au/austinjspui/handle/1/23331
DOI: 10.1159/000508125
ORCID: 0000-0002-1650-8939
PubMed URL: 32454500
Type: Journal Article
Review
Subjects: Continuous renal replacement therapies
Cytokine removal
Extracorporeal organ support
Hemoadsorption
Hemoperfusion
COVID-19
Appears in Collections:Journal articles

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