Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/20627
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dc.contributor.authorChao, Michael-
dc.contributor.authorHo, Huong-
dc.contributor.authorLim Joon, Daryl-
dc.contributor.authorChan, Yee-
dc.contributor.authorSpencer, Sandra-
dc.contributor.authorNg, Michael-
dc.contributor.authorWasiak, Jason-
dc.contributor.authorLawrentschuk, Nathan-
dc.contributor.authorMcMillan, Kevin-
dc.contributor.authorSengupta, Shomik-
dc.contributor.authorTan, Alwin-
dc.contributor.authorKoufogiannis, George-
dc.contributor.authorCokelek, Margaret-
dc.contributor.authorForoudi, Farshad-
dc.contributor.authorKhong, Tristan-Scott-
dc.contributor.authorBolton, Damien M-
dc.date2019-03-31-
dc.date.accessioned2019-04-15T05:39:50Z-
dc.date.available2019-04-15T05:39:50Z-
dc.date.issued2019-03-
dc.identifier.citationRadiation Oncology Journal 2019; 37(1): 43-50en_US
dc.identifier.issn2234-1900-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/20627-
dc.description.abstractThe aim of this retrospective study was to investigate the use of a radiopaque tissue fiducial marker (TFM) in the treatment of prostate cancer patients who undergo post-prostatectomy radiotherapy (PPRT). TFM safety, its role and benefit in quantifying the set-up uncertainties in patients undergoing PPRT image-guided radiotherapy were assessed. A total of 45 consecutive PPRT patients underwent transperineal implantation of TFM at the level of vesicourethral anastomosis in the retrovesical tissue prior to intensity-modulated radiotherapy. Prostate bed motion was calculated by measuring the position of the TFM relative to the pelvic bony anatomy on daily cone-beam computed tomography. The stability and visibility of the TFM were assessed in the initial 10 patients. No postoperative complications were recorded. A total of 3,500 images were analysed. The calculated prostate bed motion for bony landmark matching relative to TFM were 2.25 mm in the left-right, 5.89 mm in the superior-inferior, and 6.59 mm in the anterior-posterior directions. A significant 36% reduction in the mean volume of rectum receiving 70 Gy (rV70) was achieved for a uniform planning target volume (PTV) margin of 7 mm compared with the Australian and New Zealand Faculty of Radiation Oncology Genito-Urinary Group recommended PTV margin of 10 mm. The use of TFM was safe and can potentially eliminate set-up errors associated with bony landmark matching, thereby allowing for tighter PTV margins and a consequent favourable reduction in dose delivered to the bladder and rectum, with potential improvements in toxicities.en_US
dc.language.isoeng-
dc.subjectFiducial markeren_US
dc.subjectImage-guided radiotherapyen_US
dc.subjectIntensity-modulated radiotherapyen_US
dc.subjectProstate canceren_US
dc.subjectProstatectomyen_US
dc.titleThe use of tissue fiducial markers in improving the accuracy of post-prostatectomy radiotherapy.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleRadiation Oncology Journalen_US
dc.identifier.affiliationBox Hill Hospital, Box Hill, Australiaen_US
dc.identifier.affiliationThe Ringwood Private Hospital, Ringwood East, Australiaen_US
dc.identifier.affiliationThe Bays Hospital, Mornington, Australiaen_US
dc.identifier.affiliationAustin Healthen_US
dc.identifier.affiliationGenesis Cancer Care Victoria, Melbourne, Australiaen_US
dc.identifier.doi10.3857/roj.2018.00556en_US
dc.type.contentTexten_US
dc.identifier.orcid0000-0002-5145-6783en_US
dc.identifier.orcid0000-0001-8553-5618en_US
dc.identifier.orcid0000-0001-8387-0965en_US
dc.identifier.pubmedid30947480-
dc.type.austinJournal Article-
local.name.researcherBolton, Damien M
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptUrology-
crisitem.author.deptUrology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptRadiation Oncology-
crisitem.author.deptUrology-
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