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https://ahro.austin.org.au/austinjspui/handle/1/20221| Title: | Infectious Disease Transmission in Solid Organ Transplantation: Donor Evaluation, Recipient Risk, and Outcomes of Transmission. | Austin Authors: | White, Sarah L;Rawlinson, William;Boan, Peter;Sheppeard, Vicky;Wong, Germaine;Waller, Karen;Opdam, Helen I ;Kaldor, John;Fink, Michael;Verran, Deborah;Webster, Angela;Wyburn, Kate;Grayson, Lindsay;Glanville, Allan;Cross, Nick;Irish, Ashley;Coates, Toby;Griffin, Anthony;Snell, Greg;Alexander, Stephen I;Campbell, Scott;Chadban, Steven;Macdonald, Peter;Manley, Paul;Mehakovic, Eva;Ramachandran, Vidya;Mitchell, Alicia;Ison, Michael | Affiliation: | Women's and Children's Health and Biotechnology and Biomolecular Sciences, University of New South Wales Schools of Medicine, Sydney, Australia Communicable Diseases Network Australia, New South Wales Health, Sydney, Australia Departments of Infectious Diseases and Microbiology, Fiona Stanley Hospital, Perth, Australia PathWest Laboratory Medicine, Perth, Australia Lung Transplant, Alfred Health, Melbourne, Victoria, Australia Serology and Virology Division, NSW Health Pathology Prince of Wales Hospital, Sydney, Australia Kidney Disorders, Auckland District Health Board, Auckland City Hospital, Auckland, New Zealand Department of Nephrology, Canterbury District Health Board, Christchurch Hospital, Christchurch, New Zealand Department of Thoracic Medicine and Lung Transplantation, St Vincent's Hospital, Sydney, Australia Woolcock Institute of Medical Research, Sydney, Australia School of Medical and Molecular Biosciences, University of Technology, Sydney, Australia The Organ and Tissue Authority, Australian Government, Canberra, Australia Department of Cardiology, St Vincent's Hospital, Sydney, Australia St Vincent's Hospital Victor Chang Cardiac Research Institute, University of New South Wales, Sydney, Australia Central Clinical School, Sydney Medical School, The University of Sydney, Sydney, Australia Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia Department of Renal Medicine, University of Queensland at Princess Alexandra Hospital, Woolloongabba, Queensland, Australia Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia Renal Transplantation, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia Renal and Transplantation, Royal Adelaide Hospital, Adelaide, Australia Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia Department of Nephrology, Fiona Stanley Hospital, Perth, Australia Faculty of Health and Medical Sciences, UWA Medical School, The University of Western Australia, Crawley, Australia Austin Health, Heidelberg, Victoria, Australia Department of Surgery, Melbourne Medical School, The University of Melbourne, Melbourne, Australia Centre for Transplant and Renal Research, Westmead Hospital, Sydney, Australia Sydney School of Public Health, The University of Sydney, Sydney, Australia Transplantation Services, Royal Prince Alfred Hospital, Sydney, Australia Kirby Institute, University of New South Wales, Sydney, Australia Divisions of Infectious Diseases and Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL.. |
Issue Date: | Jan-2019 | Date: | 2018-12-20 | Publication information: | Transplantation direct 2019; 5(1): e416 | Abstract: | In 2016, the Transplantation Society of Australia and New Zealand, with the support of the Australian Government Organ and Tissue authority, commissioned a literature review on the topic of infectious disease transmission from deceased donors to recipients of solid organ transplants. The purpose of this review was to synthesize evidence on transmission risks, diagnostic test characteristics, and recipient management to inform best-practice clinical guidelines. The final review, presented as a special supplement in Transplantation Direct, collates case reports of transmission events and other peer-reviewed literature, and summarizes current (as of June 2017) international guidelines on donor screening and recipient management. Of particular interest at the time of writing was how to maximize utilization of donors at increased risk for transmission of human immunodeficiency virus, hepatitis C virus, and hepatitis B virus, given the recent developments, including the availability of direct-acting antivirals for hepatitis C virus and improvements in donor screening technologies. The review also covers emerging risks associated with recent epidemics (eg, Zika virus) and the risk of transmission of nonendemic pathogens related to donor travel history or country of origin. Lastly, the implications for recipient consent of expanded utilization of donors at increased risk of blood-borne viral disease transmission are considered. | URI: | https://ahro.austin.org.au/austinjspui/handle/1/20221 | DOI: | 10.1097/TXD.0000000000000852 | Journal: | Transplantation direct | PubMed URL: | 30656214 | ISSN: | 2373-8731 | Type: | Journal Article |
| Appears in Collections: | Journal articles |
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