| Title |
|
Management of Early Node-Positive Breast Cancer in Australia: A Multicentre Study. |
|
|
| Publication Date |
|
| Author(s) |
|
| Subject |
|
axillary lymph node dissection |
|
|
sentinel lymph node biopsy |
|
|
| Type of document |
|
| DOI |
|
| Abstract |
|
To examine practice patterns for breast cancer patients with limited sentinel node (SN) disease in light of the ACOSOG Z0011 results. Retrospective analysis of patients with T1-2 breast cancer and positive sentinel lymph node biopsy (SLNB) admitted between January 2009 and December 2012. Patient demographics, tumor characteristics, and treatments were recorded. Eight hundred positive SLNBs were identified. A total of 452 (56.5%) proceeded to completion axillary lymph node dissection (cALND). cALND rate decreased from 65.1% to 49.7% from 2009-2010 to 2011-2012. cALND was performed for micrometastasis or isolated tumor cells in 39.3% in 2009-2010 and 22.2% in 2011-2012, whereas for macrometastases the rates were 83.1% and 68.6%, respectively. cALND rates diminished for both Z0011-eligible and -ineligible patients. The ACOSOG Z0011 trial presentation and publication coincided with a reduction in cALND for breast cancer with limited nodal disease. There appears equipoise regarding management of macrometastatic SN disease. |
|
|
| Link |
|
| Citation |
|
The breast journal 2016; 22(4): 413-419 |
|
|
| Jornal Title |
|
