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Title: Case-fatality and functional status three months after first-ever stroke in Vietnam.
Austin Authors: Pham, Tran L;Blizzard, Leigh;Srikanth, Velandai;Thrift, Amanda G;Lien, Nguyen T K;Thang, Nguyen H;Gall, Seana L
Affiliation: Stroke Division, The Florey Institute of Neuroscience and Mental Health, Heidelberg, Australia
Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Viet Nam
Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Stroke and Ageing Research Centre, School of Clinical Sciences, Monash University, Melbourne, Australia
Stroke Unit, Cerebrovascular Disease Department, 115 People's Hospital, Ho Chi Minh City, Viet Nam
Issue Date: 15-Jun-2016 2016-03-12
Publication information: Journal of the neurological sciences 2016; 365: 65-71
Abstract: To provide novel information on outcomes after first-ever stroke in Vietnam, case-fatality and functional status were assessed 3months after stroke onset. First-ever stroke patients admitted to the stroke unit of a tertiary teaching hospital in Ho Chi Minh City, Vietnam were recruited, examined and interviewed. Functional status was assessed on the modified Rankin Scale (mRS) at admission and again at 3months. We recruited 450 consecutive first-ever stroke patients (99.6% participation, 47.9% female, mean age 62.5 [SD 14.0] years, 76.2% ischaemic stroke). Three-month observed case-fatality was 10.4%. Under plausible assumptions about deaths among non-recruited participants, the estimated case-fatality would be higher (16.4%) Those who had died were mostly older patients compromised by comorbidities and pre-existing disability, and who had severe impairment or severe disability due to stroke at the time of admission. At 3-month follow-up of 376 patients, 34% had least severe disability (mRS=0/1), 39% had intermediate disability and 28% had most severe disability (mRS=4/5). Those with least severe disability were mostly men younger than 65years of age and principally with ischemic stroke. Those with most severe disability were predominantly women aged ≥65years and those with severe disability, mainly attributable to intracerebral haemorrhage. At 3months, 50% had better functional status than at stroke onset, and 27% had poorer function. Case-fatality was relatively low in this study, possibly because of cultural preferences for end-of-life care at home. The dependency burden was relatively high, placing pressure on the healthcare system and society.
DOI: 10.1016/j.jns.2016.03.013
ORCID: 0000-0001-8533-4170
Journal: Journal of the neurological sciences
PubMed URL: 27206877
Type: Journal Article
Subjects: Case-fatality
Functional status
Appears in Collections:Journal articles

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